View : 323 Download: 0

Whole-Cell Photoenzymatic Cascades to Synthesize Long-Chain Aliphatic Amines and Esters from Renewable Fatty Acids

Title
Whole-Cell Photoenzymatic Cascades to Synthesize Long-Chain Aliphatic Amines and Esters from Renewable Fatty Acids
Authors
Cha H.-J.Hwang S.-Y.Lee D.-S.Kumar A.R.Kwon Y.-U.Voß M.Schuiten E.Bornscheuer U.T.Hollmann F.Oh D.-K.Park J.-B.
Ewha Authors
박진병권용억
SCOPUS Author ID
박진병scopus; 권용억scopus
Issue Date
2020
Journal Title
Angewandte Chemie - International Edition
ISSN
1433-7851JCR Link
Citation
Angewandte Chemie - International Edition vol. 59, no. 18, pp. 7024 - 7028
Keywords
Biocatalysisfatty acidslong-chain aliphatic aminesphotodecarboxylasewhole-cell biocatalysis
Publisher
Wiley-VCH Verlag
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
Long-chain aliphatic amines such as (S,Z)-heptadec-9-en-7-amine and 9-aminoheptadecane were synthesized from ricinoleic acid and oleic acid, respectively, by whole-cell cascade reactions using the combination of an alcohol dehydrogenase (ADH) from Micrococcus luteus, an engineered amine transaminase from Vibrio fluvialis (Vf-ATA), and a photoactivated decarboxylase from Chlorella variabilis NC64A (Cv-FAP) in a one-pot process. In addition, long chain aliphatic esters such as 10-(heptanoyloxy)dec-8-ene and octylnonanoate were prepared from ricinoleic acid and oleic acid, respectively, by using the combination of the ADH, a Baeyer–Villiger monooxygenase variant from Pseudomonas putida KT2440, and the Cv-FAP. The target compounds were produced at rates of up to 37 U g−1 dry cells with conversions up to 90 %. Therefore, this study contributes to the preparation of industrially relevant long-chain aliphatic chiral amines and esters from renewable fatty acid resources. © 2020 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
Show the fulltext
DOI
10.1002/anie.201915108
Appears in Collections:
엘텍공과대학 > 식품공학전공 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE