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Association between dietary flavanones intake and lipid profiles according to the presence of metabolic syndrome in Korean women with type 2 diabetes mellitus
- Title
- Association between dietary flavanones intake and lipid profiles according to the presence of metabolic syndrome in Korean women with type 2 diabetes mellitus
- Authors
- Oh J.S.; Kim H.; Vijayakumar A.; Kwon O.; Choi Y.J.; Huh K.B.; Chang N.
- Ewha Authors
- 장남수; 권오란; 김혜숙
- SCOPUS Author ID
- 장남수; 권오란; 김혜숙
- Issue Date
- 2016
- Journal Title
- Nutrition Research and Practice
- ISSN
- 1976-1457
- Citation
- Nutrition Research and Practice vol. 10, no. 1, pp. 67 - 73
- Keywords
- Apolipoprotein; Flavanones; Metabolic syndrome; T2DM
- Publisher
- Korean Nutrition Society
- Indexed
- SCIE; SCOPUS; KCI
- Document Type
- Article
- Abstract
- BACKGROUND/OBJECTIVES: This study was aimed at examining the association between dietary flavanones intake and lipid profiles according to the presence of metabolic syndrome (MetS) in Korean women with type 2 diabetes mellitus (T2DM). SUBJECTS/METHODS: A cross-sectional analysis was performed among 502 female T2DM patients (non-MetS group; n = 129, MetS group; n = 373) who were recruited from the Huh’s Diabetes Clinic in Seoul, Korea between 2005 and 2011. The dietary intake was assessed by a validated semi-quantitative food frequency questionnaire (FFQ) and the data was analyzed using the Computer Aided Nutritional Analysis program (CAN-Pro) version 4.0 software. The intake of flavanones was estimated on the basis of the flavonoid database. RESULTS: In the multiple linear regression analysis after adjustment for confounding factors, daily flavanones intake was negatively associated with CVD risk factors such as total cholesterol, LDL-cholesterol, and apoB and apoB/apoA1 ratio only in the MetS group but not in the non-MetS group. Multiple logistic regression analysis revealed that the odds ratio for a higher apoB/apoA1 ratio above the median (≥ 0.74) was significantly low in the 4th quartile compared to that in the 1st quartile of dietary flavanones intake [OR: 0.477, 95% CI: 0.255-0.894, P for trend = 0.0377] in the MetS group. CONCLUSIONS: Dietary flavanones intake was inversely associated with the apoB/apoA1 ratio, suggesting a potential protective effect of flavanones against CVD in T2DM women with MetS. © 2016 The Korean Nutrition Society and the Korean Society of Community Nutrition.
- DOI
- 10.4162/nrp.2016.10.1.67
- Appears in Collections:
- 신산업융합대학 > 식품영양학과 > Journal papers
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