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Effect of Chlorella vulgaris intake on antioxidative capacity in rats oxidatively stressed with dietary cadmium

Title
Effect of Chlorella vulgaris intake on antioxidative capacity in rats oxidatively stressed with dietary cadmium
Authors
Kim Y.J.Jeong S.Kwon S.Kim M.K.
Ewha Authors
김미경정세원
SCOPUS Author ID
김미경scopusscopus; 정세원scopus
Issue Date
2009
Journal Title
Food Science and Biotechnology
ISSN
1226-7708JCR Link
Citation
vol. 18, no. 5, pp. 1055 - 1062
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
This study was conducted to investigate whether dietary chlorella intake could have an effect on antioxidative capacity in rats oxidatively stressed with cadmium (Cd). Sprague-Dawley rats fed dietary chlorella (0, 5, and 10%) for 4 weeks after induction of oxidative stress by exposing to Cd (200 ppm) for 8 weeks. After the oxidative stress applied, plasma and liver malondialdehyde concentrations and xanthine oxidase activities were decreased in 5% chlorella fed group compared to chlorella free group. Although liver heme oxygenase-1 protein expression was not affected by chlorella, the enzyme activity was improved in 5% chlorella fed group. Erythrocyte superoxide dismutase activity and hepatic metallothionein concentration were increased in 5% chlorella fed group. However, 10% chlorella intake had no effect on the improvement of oxidative stress-related enzymes and proteins. These findings suggest that, after induction of oxidative stress with Cd, 5% chlorella intake might improve antioxidative capacity against oxidative stress. © The Korean Society of Food Science and Technology.
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신산업융합대학 > 식품영양학과 > Journal papers
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