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Spectroscopic methods to analyze drug metabolites

Title
Spectroscopic methods to analyze drug metabolites
Authors
Yi J.-J.Park K.Kim W.-J.Rhee J.-K.Son W.S.
Ewha Authors
이진규
SCOPUS Author ID
이진규scopus
Issue Date
2018
Journal Title
Archives of Pharmacal Research
ISSN
0253-6269JCR Link
Citation
Archives of Pharmacal Research vol. 41, no. 4, pp. 355 - 371
Keywords
Circular dichroismDrug metabolitesInfrared spectroscopyMass spectrometryNuclear magnetic resonanceRaman spectroscopySpectroscopySurface plasmon resonanceUltraviolet–visible spectroscopy
Publisher
Pharmaceutical Society of Korea
Indexed
SCIE; SCOPUS; KCI WOS scopus
Document Type
Review
Abstract
Drug metabolites have been monitored with various types of newly developed techniques and/or combination of common analytical methods, which could provide a great deal of information on metabolite profiling. Because it is not easy to analyze whole drug metabolites qualitatively and quantitatively, a single solution of analytical techniques is combined in a multilateral manner to cover the widest range of drug metabolites. Mass-based spectroscopic analysis of drug metabolites has been expanded with the help of other parameter-based methods. The current development of metabolism studies through contemporary pharmaceutical research are reviewed with an overview on conventionally used spectroscopic methods. Several technical approaches for conducting drug metabolic profiling through spectroscopic methods are discussed in depth. © 2018, The Pharmaceutical Society of Korea.
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DOI
10.1007/s12272-018-1010-x
Appears in Collections:
엘텍공과대학 > 식품공학전공 > Journal papers
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