Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 장남수 | - |
dc.date.accessioned | 2016-08-28T12:08:42Z | - |
dc.date.available | 2016-08-28T12:08:42Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1976-1457 | - |
dc.identifier.other | OAK-7600 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/221641 | - |
dc.description.abstract | We investigated the effect of paternal folate status on folate content and expression of the folate transporter folate receptor α (FRα) in rat placental tissues. Rats were mated after males were fed a diet containing 0 mg of folic acid/kg of diet (paternal folate-deficient, PD) or 8 mg folic acid/kg of diet (paternal folate-supplemented, PS) for 4 weeks. At 20 days of gestation, the litter size, placental weight, and fetal weight were measured, and placental folate content (n = 8/group) and expression of FRα (n = 10/group) were analyzed by microbiological assay and Western blot analysis, respectively. Although there was no difference observed in litter size or fetal weight, but significant reduction (10%) in the weight of the placenta was observed in the PD group compared to that in the PS group. In the PD group, placental folate content was significantly lower (by 35%), whereas FRα expression was higher (by 130%) compared to the PS group. Our results suggest that paternal folate status plays a critical role in regulating placental folate metabolism and transport. © 2011 The Korean Nutrition Society and the Korean Society of Community Nutrition. | - |
dc.language | English | - |
dc.title | Effect of paternal folate deficiency on placental folate content and folate receptor α expression in rats | - |
dc.type | Article | - |
dc.relation.issue | 2 | - |
dc.relation.volume | 5 | - |
dc.relation.index | SCIE | - |
dc.relation.index | SCOPUS | - |
dc.relation.index | KCI | - |
dc.relation.startpage | 112 | - |
dc.relation.lastpage | 116 | - |
dc.relation.journaltitle | Nutrition Research and Practice | - |
dc.identifier.doi | 10.4162/nrp.2011.5.2.112 | - |
dc.identifier.wosid | WOS:000290362200004 | - |
dc.identifier.scopusid | 2-s2.0-79956284588 | - |
dc.author.google | Kim H.W. | - |
dc.author.google | Choi Y.J. | - |
dc.author.google | Kim K.N. | - |
dc.author.google | Tamura T. | - |
dc.author.google | Chang N. | - |
dc.contributor.scopusid | 장남수(7202467832;56447965800) | - |
dc.date.modifydate | 20220119163241 | - |