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dc.contributor.author김미경-
dc.date.accessioned2016-08-27T02:08:00Z-
dc.date.available2016-08-27T02:08:00Z-
dc.date.issued2009-
dc.identifier.issn1976-1457-
dc.identifier.otherOAK-5713-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/216350-
dc.description.abstractThe aim of this study was to examine the hypoglycemic effect of chlorella in 6 week-old type 2 diabetic Goto-Kakizaki (GK. n=30) rats and 6 week-old normal Wistar (n=30) rats. Animals were randomly assigned to 3 groups respectively, and were fed three different experimental diets containing 0%, 3% or 5% (w/w) chlorella for 8 weeks. fit diabetic GK rats, the insulinogenic-indices were not significantly different among the groups. The concentrations of fasting plasma glucagon and hepatic triglyceride, and the insulin/glucagon ratios of the GK-3% chlorella and GK-5% chlorella groups were significantly lower than those of the GK-control group. The HOMA-index and the concentrations of lasting blood glucose and plasma insulin of the GK-3% chlorella and GK-5% chlorella groups were slightly lower than those of the GK-control group. In normal Wistar rats, the insulinogenic-indices were not significantly different among the normal groups, but that of the Wistar-5% chlorella group was slightly higher than the other groups. The concentrations of fasting blood glucose and plasma insulin, and the HOMA-index of the Wistar-5% chlorella group were a little higher, and the fasting plasma glucagon concentration and the insulin/glucagon ratio of the Wistar-5% chlorella group were significantly higher than those of the Wistar-control and Wistar-3% chlorella groups. In conclusion, this study shows that the glucose-stimulated insulin secretion was not affected by the intake of chlorella, which could be beneficial. however, in improving insulin sensitivity in type 2 diabetic GK and normal Wistar rats.-
dc.languageEnglish-
dc.publisherKOREAN NUTRITION SOC-
dc.subjectChlorella-
dc.subjectglucagon-
dc.subjectGoto-kakizaki rat-
dc.subjectinsulin-
dc.subjectinsulin sensitivity-
dc.titleHypoglycemic effect of Chlorella vulgaris intake in type 2 diabetic Goto-Kakizaki and normal Wistar rats-
dc.typeArticle-
dc.relation.issue1-
dc.relation.volume3-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.indexKCI-
dc.relation.startpage23-
dc.relation.lastpage30-
dc.relation.journaltitleNUTRITION RESEARCH AND PRACTICE-
dc.identifier.doi10.4162/nrp.2009.3.1.23-
dc.identifier.wosidWOS:000267228500004-
dc.author.googleJeong, Hyejin-
dc.author.googleKwon, Hye Jin-
dc.author.googleKim, Mi Kyung-
dc.contributor.scopusid김미경(26029895800;56372953900)-
dc.date.modifydate20180104081001-
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신산업융합대학 > 식품영양학과 > Journal papers
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