Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 박윤정 | * |
dc.date.accessioned | 2024-02-06T16:31:28Z | - |
dc.date.available | 2024-02-06T16:31:28Z | - |
dc.date.issued | 2023 | * |
dc.identifier.issn | 2072-6643 | * |
dc.identifier.other | OAK-34442 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/267101 | - |
dc.description.abstract | It has emerged the gut microbiome is crucially linked to metabolic health and obesity. Macronutrient distribution has been discussed as a key parameter in weight-loss programs, but little is known about its impact on the gut microbiome. We investigated the effects of weight-loss meal replacement programs with different macronutrient ratios on the gut microbiota and metabolic parameters in subjects with overweight and obesity. Three low-calorie meal replacement programs with different ratios of carbohydrates, proteins, and lipids were designed: a balanced diet (Group B, 60:15:30), a high-lipid−low-carbohydrate diet (Group F, 35:20:55), and a protein-enriched diet (Group P, 40:25:35). Sixty overweight or obese participants were provided with the meals twice daily for 3 weeks. In all groups, diet intervention resulted in reduced body weight and BMI. The relative abundance of Bacteroidetes and Firmicutes phyla decreased and increased, respectively, which increased the Firmicutes/Bacteroidetes (F/B) ratio in all subjects, particularly in Groups B and P. Alpha- and beta-diversity were augmented at the phylum level in Group P. In conclusion, short-term interventions with weight-loss meal replacement programs increased butyrate-producing bacteria and the F/B ratio. Moreover, the protein-enriched diet significantly increased alpha- and beta-diversity compared to the balanced diet and the high-lipid−low-carbohydrate diet. © 2023 by the authors. | * |
dc.language | English | * |
dc.publisher | Multidisciplinary Digital Publishing Institute (MDPI) | * |
dc.subject | calorie restriction | * |
dc.subject | gut microbiome | * |
dc.subject | macronutrient distribution | * |
dc.subject | meal replacement | * |
dc.subject | short-term dietary intervention | * |
dc.title | Short-Term Effects of Weight-Loss Meal Replacement Programs with Various Macronutrient Distributions on Gut Microbiome and Metabolic Parameters: A Pilot Study | * |
dc.type | Article | * |
dc.relation.issue | 22 | * |
dc.relation.volume | 15 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | Nutrients | * |
dc.identifier.doi | 10.3390/nu15224744 | * |
dc.identifier.wosid | WOS:001114004100001 | * |
dc.identifier.scopusid | 2-s2.0-85177770181 | * |
dc.author.google | Song | * |
dc.author.google | Seungmin | * |
dc.author.google | Shon | * |
dc.author.google | Jinyoung | * |
dc.author.google | Yang | * |
dc.author.google | Woo-Ri | * |
dc.author.google | Kang | * |
dc.author.google | Han-Bit | * |
dc.author.google | Kim | * |
dc.author.google | Keun-Ha | * |
dc.author.google | Park | * |
dc.author.google | Ju-Yeon | * |
dc.author.google | Lee | * |
dc.author.google | Sanghoo | * |
dc.author.google | Baik | * |
dc.author.google | Sae Yun | * |
dc.author.google | Kyoung-Ryul | * |
dc.author.google | Yoon Jung | * |
dc.contributor.scopusid | 박윤정(55494373100) | * |
dc.date.modifydate | 20240215164841 | * |