Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 박지훈 | * |
dc.date.accessioned | 2023-04-14T16:31:05Z | - |
dc.date.available | 2023-04-14T16:31:05Z | - |
dc.date.issued | 2023 | * |
dc.identifier.issn | 2073-4360 | * |
dc.identifier.other | OAK-33186 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/264828 | - |
dc.description.abstract | One-step fabrication method for thin films and shells is developed with nature-derived eggshell membrane hydrolysates (ESMHs) and coffee melanoidins (CMs) that have been discarded as food waste. The nature-derived polymeric materials, ESMHs and CMs, prove highly biocompatible with living cells, and the one-step method enables cytocompatible construction of cell-in-shell nanobiohybrid structures. Nanometric ESMH-CM shells are formed on individual probiotic Lactobacillus acidophilus, without any noticeable decrease in viability, and the ESMH-CM shells effectively protected L. acidophilus in the simulated gastric fluid (SGF). The cytoprotection power is further enhanced by Fe3+-mediated shell augmentation. For example, after 2 h of incubation in SGF, the viability of native L. acidophilus is 30%, whereas nanoencapsulated L. acidophilus, armed with the Fe3+-fortified ESMH-CM shells, show 79% in viability. The simple, time-efficient, and easy-to-process method developed in this work would contribute to many technological developments, including microbial biotherapeutics, as well as waste upcycling. | * |
dc.language | English | * |
dc.publisher | MDPI | * |
dc.subject | coffee melanoidins | * |
dc.subject | eggshell membrane hydrolysates | * |
dc.subject | Lactobacillus acidophilus | * |
dc.subject | single-cell nanoencapsulation | * |
dc.subject | probiotics | * |
dc.title | Cytoprotection of Probiotic Lactobacillus acidophilus with Artificial Nanoshells of Nature-Derived Eggshell Membrane Hydrolysates and Coffee Melanoidins in Single-Cell Nanoencapsulation | * |
dc.type | Article | * |
dc.relation.issue | 5 | * |
dc.relation.volume | 15 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | POLYMERS | * |
dc.identifier.doi | 10.3390/polym15051104|http://dx.doi.org/10.3390/polym15051104 | * |
dc.identifier.wosid | WOS:000948016400001 | * |
dc.identifier.scopusid | 2-s2.0-85149744239 | * |
dc.author.google | Han, Sang Yeong | * |
dc.author.google | Nguyen, Duc Tai | * |
dc.author.google | Kim, Beom Jin | * |
dc.author.google | Kim, Nayoung | * |
dc.author.google | Kang, Eunhye K. | * |
dc.author.google | Park, Ji Hun | * |
dc.author.google | Choi, Insung S. | * |
dc.contributor.scopusid | 박지훈(57202217665) | * |
dc.date.modifydate | 20240308130150 | * |