Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤주영 | * |
dc.date.accessioned | 2022-11-03T16:31:09Z | - |
dc.date.available | 2022-11-03T16:31:09Z | - |
dc.date.issued | 2022 | * |
dc.identifier.issn | 0956-5663 | * |
dc.identifier.issn | 1873-4235 | * |
dc.identifier.other | OAK-32442 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/262896 | - |
dc.description.abstract | Theranostic, which integrates the diagnosis and tumor treatment in tandem, is an emerging strategy in cancer treatment. Here, we report a novel and unique theranostic nanoparticle, HBCP NP, based on hexa-BODIPY cyclophosphazene (HBCP). Due to the unique bulky molecular structure of HBCP, this nanoparticle can simultaneously perform near-infrared (NIR) fluorescence imaging and photoacoustic imaging (PAI). Interestingly, since reactive oxygen species (ROS) generation of HBCP NPs is completely inhibited, `safe' fluorescence imaging is possible without the risk of cell damage even under laser irradiation. Finally, NIR fluorescence imaging and PAI in 4T1 tumor-bearing mice demonstrated selective accumulation of HBCP NPs at tumor sites. In addition, HBCP NPs exhibited excellent photothermal effects under high-power laser irradiation, achieving effective tumor growth inhibition. | * |
dc.language | English | * |
dc.publisher | ELSEVIER ADVANCED TECHNOLOGY | * |
dc.subject | NIR fluorescence Imaging | * |
dc.subject | Photoacoustic imaging | * |
dc.subject | Dual-modal imaging | * |
dc.subject | Photothermal cancer therapy | * |
dc.subject | Theragnostic nanoparticle | * |
dc.title | Hexa-BODIPY-cyclotriphosphazene based nanoparticle for NIR fluorescence/photoacoustic dual-modal imaging and photothermal cancer therapy | * |
dc.type | Article | * |
dc.relation.volume | 216 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | BIOSENSORS & BIOELECTRONICS | * |
dc.identifier.doi | 10.1016/j.bios.2022.114612 | * |
dc.identifier.wosid | WOS:000908577400004 | * |
dc.identifier.scopusid | 2-s2.0-85135726499 | * |
dc.author.google | Kwon, Nahyun | * |
dc.author.google | Kim, Kwang H. | * |
dc.author.google | Park, Sinyoung | * |
dc.author.google | Cho, Yejin | * |
dc.author.google | Park, Eun-Yeong | * |
dc.author.google | Lim, Junha | * |
dc.author.google | Cetindere, Seda | * |
dc.author.google | Tumay, Sureyya Oguz | * |
dc.author.google | Kim, Won Jong | * |
dc.author.google | Li, Xingshu | * |
dc.author.google | Nam, Ki Taek | * |
dc.author.google | Kim, Chulhong | * |
dc.author.google | Yesilot, Serkan | * |
dc.author.google | Yoon, Juyoung | * |
dc.contributor.scopusid | 윤주영(7403587371) | * |
dc.date.modifydate | 20240118162450 | * |