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DNA polymorphism in the Adh region of Drosophila melanogaster in Korea

Title
DNA polymorphism in the Adh region of Drosophila melanogaster in Korea
Authors
Park K.S.Lim M.Y.Suh D.S.Kang S.J.
Ewha Authors
강순자임미연
SCOPUS Author ID
강순자scopusscopus; 임미연scopus
Issue Date
1996
Journal Title
Molecules and Cells
ISSN
1016-8478JCR Link
Citation
Molecules and Cells vol. 6, no. 6, pp. 673 - 678
Indexed
SCI; SCIE; SCOPUS; KCI scopus
Document Type
Article
Abstract
The alcohol dehydrogenase (ADH; alcohol: NAD+ oxidoreductase: EC1.1.1.1) activity was measured and restriction mapping about the Adh region was performed to assess DNA polymorphism in Drosophila melanogaster populations of Korea in 24 iso-second chromosome lines: 10 lines from the Chunan population and 14 lines from the Pusan population. The mean ADH activity in AdhF lines was 3.5 fold higher than that of AdhS lines. The mean ADH activity in the Chunan population was higher than that of the Pusan population. Polymorphism due to both restriction site presense/absence and insertion/deletion was detected. One restriction site polymorphism, 2 kinds of insertions, and 3 kinds of deletions were observed. It was concluded that DNA polymorphism in the Adh DNA region is present in Korean populations of Drosophila melanogaster. The overall heterozygosity in Korean populations of Drosophila melanogaster was 0.843. A strong linkage disequilibrium between BamHI (- 7.0) and Adh allotype and between D-2 deletion and Adh allotype was observed. This suggests that the mutation occurred in Adh alleles on a chromosome lacking the BamHI (- 7.0).
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사범대학 > 과학교육과 > Journal papers
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