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Acute intake of mulberry leaf aqueous extract affects postprandial glucose response after maltose loading: Randomized double-blind placebo-controlled pilot study

Title
Acute intake of mulberry leaf aqueous extract affects postprandial glucose response after maltose loading: Randomized double-blind placebo-controlled pilot study
Authors
Chung H.I.Kim J.Kim J.Y.Kwon O.
Ewha Authors
권오란김주희
SCOPUS Author ID
권오란scopus; 김주희scopusscopus
Issue Date
2013
Journal Title
Journal of Functional Foods
ISSN
1756-4646JCR Link
Citation
vol. 5, no. 3, pp. 1502 - 1506
Indexed
SCIE; SCOPUS WOS scopus
Abstract
Mulberry leaf extract was investigated as a potent alpha-glucosidase inhibitor, especially for individuals with prediabetes. We evaluated the effect of the ingestion of mulberry leaf aqueous extract (MLAE) on postprandial glucose responses in healthy subjects. We carried out a randomized, double-blind, placebo-controlled trial to determine the intake amount of MLAE (1.25, 2.5, or 5. g) and time necessary to impact postprandial blood glucose levels after 75. g of maltose loading in 50 healthy subjects. Ingestion of MLAE led to a decrease in postchallenge acute glucose levels following intake of 2.5 or 5. g of MLAE at 30 and 60. min (P = 0.0137 and 0.0423, respectively). There was no significant difference between pre- and simultaneous administration of MLAE. The ingestion of MLAE resulted in improved postprandial glycemic control in healthy subjects. © 2013 Elsevier Ltd.
DOI
10.1016/j.jff.2013.04.015
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신산업융합대학 > 식품영양학과 > Journal papers
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