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Relationship between milk and calcium intake and lipid metabolism in female patients with type 2 diabetes
- Relationship between milk and calcium intake and lipid metabolism in female patients with type 2 diabetes
- Kim J.; Hwang J.-Y.; Kim K.N.; Choi Y.-J.; Chang N.; Huh K.-B.
- Ewha Authors
- 장남수; 김기남
- SCOPUS Author ID
- Issue Date
- Journal Title
- Yonsei Medical Journal
- vol. 54, no. 3, pp. 626 - 636
- SCI; SCIE; SCOPUS; KCI
- Purpose: This study was conducted to determine the association between intake of milk and dairy products as well as calcium and biomarkers related to lipid metabolism in Korean female patients with type 2 diabetes. Materials and Methods: A cohort of 509 female subjects (mean age: 59.0 years; range: 35-80 years) was recruited from Huh's Diabetes Clinic in Seoul between 2005 and 2010. Dietary intake was assessed using a validated food-frequency questionnaire. Subjects were divided into three groups on the basis of their daily intake of milk and dairy products [<50 g/day (0<50 g/day), 50-200 g/day, and >200 g/day (>200-1201 g/day)] and then further divided into two groups according to their daily calcium intake: below and above the estimated average requirement (EAR). Results: After adjustment for age, body mass index, energy intake, exercise, use of nutritional supplements and cholesterol medication, the level of serum high-density lipoprotein (HDL)-cholesterol was significantly higher in subjects with milk and dairy products consumption of >200 g/day than in subjects in the other two groups. Those subjects with a milk and dairy products consumption of >200 g/day had significantly higher levels of apolipoprotein A-1 and a significantly lower atherogenic index than the other two groups. Patients with a calcium intake above the EAR exhibited a significantly greater serum HDL-cholesterol level than those with a calcium intake below the EAR. Conclusion: Milk and dairy products, good sources of calcium, play a positive role in lipid profiles in female patients with type 2 diabetes. © Yonsei University College of Medicine 2013.
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