DSpace at EWHA: 2,6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure-activity relationship, and docking study

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DC Field	Value	Language
dc.contributor.author	권영주	*
dc.date.accessioned	2016-08-28T12:08:38Z	-
dc.date.available	2016-08-28T12:08:38Z	-
dc.date.issued	2010	*
dc.identifier.issn	0960-894X	*
dc.identifier.other	OAK-6150	*
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/220423	-
dc.description.abstract	For the development of novel antitumor agents, 2,6-dithienyl-4-furyl pyridine derivatives were prepared and evaluated for their topoisomerase I and II inhibitory activity as well as cytotoxicity against several human cancer cell lines. Among the 21 prepared compounds, compound 24 exhibited strong topoisomerase I inhibitory activity. In addition, a docking study with topoisomerase I and compound 24 was performed. © 2009 Elsevier Ltd. All rights reserved.	*
dc.language	English	*
dc.title	2,6-Dithienyl-4-furyl pyridines: Synthesis, topoisomerase I and II inhibition, cytotoxicity, structure-activity relationship, and docking study	*
dc.type	Article	*
dc.relation.issue	1	*
dc.relation.volume	20	*
dc.relation.index	SCI	*
dc.relation.index	SCIE	*
dc.relation.index	SCOPUS	*
dc.relation.startpage	42	*
dc.relation.lastpage	47	*
dc.relation.journaltitle	Bioorganic and Medicinal Chemistry Letters	*
dc.identifier.doi	10.1016/j.bmcl.2009.11.041	*
dc.identifier.wosid	WOS:000272935600005	*
dc.identifier.scopusid	2-s2.0-72049125310	*
dc.author.google	Basnet A.	*
dc.author.google	Thapa P.	*
dc.author.google	Karki R.	*
dc.author.google	Choi H.	*
dc.author.google	Choi J.H.	*
dc.author.google	Yun M.	*
dc.author.google	Jeong B.-S.	*
dc.author.google	Jahng Y.	*
dc.author.google	Na Y.	*
dc.author.google	Cho W.-J.	*
dc.author.google	Kwon Y.	*
dc.author.google	Lee C.-S.	*
dc.author.google	Lee E.-S.	*
dc.contributor.scopusid	권영주(12446435600)	*
dc.date.modifydate	20240422124907	*