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The role of a second protein (Des VIII) in glycosylation for the biosynthesis of hybrid macrolide antibiotics in Streptomyces venezuelae

Title
The role of a second protein (Des VIII) in glycosylation for the biosynthesis of hybrid macrolide antibiotics in Streptomyces venezuelae
Authors
Hong J.S.Kim W.S.Lee S.K.Koh H.S.Park H.S.Park S.J.Kim Y.S.Yoon Y.J.
Ewha Authors
윤여준김연상
SCOPUS Author ID
윤여준scopus
Issue Date
2005
Journal Title
Journal of Microbiology and Biotechnology
ISSN
1017-7825JCR Link
Citation
vol. 15, no. 3, pp. 640 - 645
Indexed
SCIE; SCOPUS; KCI WOS scopus
Abstract
The function of the desVIII gene in the pikromycin producer Streptomyces venezuelae was characterized by gene deletion and complementation analysis. In addition to the DesVII glycosyltransferase, the desVIII gene that has previously been suggested to be required for the incorporation of endogenous. deoxysugar, TDP-D-desosamine, into the aglycone of pikromycin is also required for the transfer of exogenous deoxysugars, TDP-D-quinovose and TDP-D-olivose. © The Korean Society for Microbiology and Biotechnology.
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자연과학대학 > 화학·나노과학전공 > Journal papers
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