Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김미경 | * |
dc.date.accessioned | 2016-08-27T02:08:00Z | - |
dc.date.available | 2016-08-27T02:08:00Z | - |
dc.date.issued | 2009 | * |
dc.identifier.issn | 1976-1457 | * |
dc.identifier.other | OAK-5713 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/216350 | - |
dc.description.abstract | The aim of this study was to examine the hypoglycemic effect of chlorella in 6 week-old type 2 diabetic Goto-Kakizaki (GK. n=30) rats and 6 week-old normal Wistar (n=30) rats. Animals were randomly assigned to 3 groups respectively, and were fed three different experimental diets containing 0%, 3% or 5% (w/w) chlorella for 8 weeks. fit diabetic GK rats, the insulinogenic-indices were not significantly different among the groups. The concentrations of fasting plasma glucagon and hepatic triglyceride, and the insulin/glucagon ratios of the GK-3% chlorella and GK-5% chlorella groups were significantly lower than those of the GK-control group. The HOMA-index and the concentrations of lasting blood glucose and plasma insulin of the GK-3% chlorella and GK-5% chlorella groups were slightly lower than those of the GK-control group. In normal Wistar rats, the insulinogenic-indices were not significantly different among the normal groups, but that of the Wistar-5% chlorella group was slightly higher than the other groups. The concentrations of fasting blood glucose and plasma insulin, and the HOMA-index of the Wistar-5% chlorella group were a little higher, and the fasting plasma glucagon concentration and the insulin/glucagon ratio of the Wistar-5% chlorella group were significantly higher than those of the Wistar-control and Wistar-3% chlorella groups. In conclusion, this study shows that the glucose-stimulated insulin secretion was not affected by the intake of chlorella, which could be beneficial. however, in improving insulin sensitivity in type 2 diabetic GK and normal Wistar rats. | * |
dc.language | English | * |
dc.publisher | KOREAN NUTRITION SOC | * |
dc.subject | Chlorella | * |
dc.subject | glucagon | * |
dc.subject | Goto-kakizaki rat | * |
dc.subject | insulin | * |
dc.subject | insulin sensitivity | * |
dc.title | Hypoglycemic effect of Chlorella vulgaris intake in type 2 diabetic Goto-Kakizaki and normal Wistar rats | * |
dc.type | Article | * |
dc.relation.issue | 1 | * |
dc.relation.volume | 3 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.index | KCI | * |
dc.relation.startpage | 23 | * |
dc.relation.lastpage | 30 | * |
dc.relation.journaltitle | NUTRITION RESEARCH AND PRACTICE | * |
dc.identifier.doi | 10.4162/nrp.2009.3.1.23 | * |
dc.identifier.wosid | WOS:000267228500004 | * |
dc.author.google | Jeong, Hyejin | * |
dc.author.google | Kwon, Hye Jin | * |
dc.author.google | Kim, Mi Kyung | * |
dc.contributor.scopusid | 김미경(56372953900;58636726700) | * |
dc.date.modifydate | 20240415130440 | * |