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Showing results 14 to 43 of 66

Issue DateTitleAuthor(s)Type
2004Design, synthesis, and biological evaluation of novel 2-pyridinyl-[1,2,4] triazoles as inhibitors of transforming growth factor β1 type 1 receptor김대기Article
2007Development of 4(5)-(6-alkylpyridin-2-yl)imidazoles as transforming growth factor-beta type1 receptor kinase inhibitors as anti-fibrotic agents김대기Meeting Abstract
2007Development of LC/MS/MS assay for the determination of 5-ethyl-2-{5-[4-(2-hydroxyethyl)piperazine-1-sulfonyl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one (SK3530) in human plasma: application to a clinical pharmacokinetic study김대기Article
2014Discovery of N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin- 2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent신윤용; 이화정; 김대기Article
2008Effect of IN-1130, a Small Molecule Inhibitor of Transforming Growth Factor-beta Type I Receptor/Activin Receptor-Like Kinase-5, on Prostate Cancer Cells신윤용; 김대기Article
2001Effect of SKI 306X, a New herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study노권재; 김대기Article
2004Estrogen receptor enhances the anti proliferative effects of trichostatin a and HC-toxin in human breast cancer cells신윤용; 김대기Article
2011EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung신윤용; 김대기Article
2018EW-7197 eluting nano-fiber covered self-expandable metallic stent to prevent granulation tissue formation in a canine urethral model김대기Article
2014EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling신윤용; 김대기; 우현애Article in Press
2014EW-7197, a novel ALK-5 kinase inhibitor, potently inhibits breast to lung metastasis신윤용; 김대기Article
2017EW-7197, an activin-like kinase 5 inhibitor, suppresses granulation tissue after stent placement in rat esophagus김대기Article
2018EW-7197, an oral transforming growth factor beta type I receptor kinase inhibitor, for preventing peritoneal adhesion formation in a rat model김대기Article
2011EW-7203, a novel small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor/activin receptor-like kinase-5, blocks TGF-β1-mediated epithelial-to-mesenchymal transition in mammary epithelial cells신윤용; 김대기Article
2007Glia-dependent TGF-β signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis김대기Article
2004HDAC inhibitor stimulate CYP3A4 proximal activity in Hepa I and HepG2 cells신윤용; 김대기Meeting Abstract
2004Histone deacetylase inhibitor stimulate CYP3A4 proximal promoter activity in HepG2 cells신윤용; 김대기Article
2008Identification of human cytochrome P450 enzymes involved in the metabolism of IN-1130, a novel activin receptor-like kinase-5 (ALK5) inhibitor신윤용; 김대기Article
2009IN-1130, a novel transforming growth factor-β type I receptor kinase (Activin Receptor-like Kinase 5) inhibitor, promotes regression of fibrotic plaque and corrects penile curvature in a rat model of Peyronie's disease김대기Article
2006IN-1130, a novel transforming growth factor-β type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy신윤용; 김대기Article
2010IN-1233, an ALK-5 inhibitor: Prevention of granulation tissue formation after bare metallic stent placement in a rat urethral model김대기Article
2013IN-1233-eluting covered metallic stent to prevent hyperplasia: Experimental study in a rabbit esophageal model김대기Article
2011Increased transforming growth factor beta 1 expression mediates ozone-induced airway fibrosis in mice김대기Article
2006MMTV/c-Neu transgenic mice as a model to study antitumor activity against breast cancer in vivo신윤용; 김대기Meeting Abstract
2010Novel ALK5 Inhibitor Inhibits Breast Tumor Metastasis and Increases the Interactions of SnoN and Ski to the Promoters of TGF beta Target Genes.신윤용; 김대기Meeting Abstract
2016Novel oral transforming growth factor- signaling inhibitor EW-7197 eradicates CML-initiating cells신윤용; 김대기Article
2009Ozone Induces Pulmonary Fibrosis via a TGF-beta Signaling Pathway김대기Meeting Abstract
2008Pharmacokinetics and tissue distribution of 3-((5-(6-methylpyridin-2-yl)-4- (quinoxalin-6-yl)-1H-imidazol-2-yl)methyl)benzamide; a novel ALK5 inhibitor and a potential anti-fibrosis drug신윤용; 이화정; 김대기Article
2015Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in T(H)17 differentiation김대기Article