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Discovery of N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin- 2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent

Title
Discovery of N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin- 2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent
Authors
Jin C.H.Krishnaiah M.Sreenu D.Subrahmanyam V.B.Rao K.S.Lee H.J.Park S.-J.Park H.-J.Lee K.Sheen Y.Y.Kim D.-K.
Ewha Authors
신윤용이화정김대기
SCOPUS Author ID
신윤용scopus; 이화정scopus; 김대기scopus
Issue Date
2014
Journal Title
Journal of Medicinal Chemistry
ISSN
1520-4804JCR Link
Citation
vol. 57, no. 10, pp. 4213 - 4238
Publisher
American Chemical Society
Indexed
SCOPUS WOS scopus
DOI
10.1021/jm500115w
Appears in Collections:
약학대학 > 약학과 > Journal papers
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