2023 | Beneficial Effects of a Curcumin Derivative and Transforming Growth Factor-β Receptor I Inhibitor Combination on Nonalcoholic Steatohepatitis | 김대기 | Article |
2017 | Cancer upregulated gene 2 induces epithelial-mesenchymal transition of human lung cancer cells via TGF-beta signaling | 김대기 | Article |
2015 | Combinatorial TGF-beta attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells | 신윤용; 김대기; 임우성 | Article |
2015 | Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells | 신윤용; 김대기; 임우성 | Article |
2004 | Design, synthesis, and biological evaluation of novel 2-pyridinyl-[1,2,4] triazoles as inhibitors of transforming growth factor β1 type 1 receptor | 김대기 | Article |
2007 | Development of 4(5)-(6-alkylpyridin-2-yl)imidazoles as transforming growth factor-beta type1 receptor kinase inhibitors as anti-fibrotic agents | 김대기 | Meeting Abstract |
2007 | Development of LC/MS/MS assay for the determination of 5-ethyl-2-{5-[4-(2-hydroxyethyl)piperazine-1-sulfonyl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one (SK3530) in human plasma: application to a clinical pharmacokinetic study | 김대기 | Article |
2023 | Different routes of administering EW-7197 versus EW-7197⋅HBr for preventing peritoneal adhesion in a rat model | 김대기 | Article |
2022 | Discovery of (E)-3-(3-((2-Cyano-4' -dimethylaminobiphenyl-4-ylmethyl)cyclohexanecarbonylamino)-5-fluorophenyl)acrylic Acid Methyl Ester, an Intestine-Specific, FXR Partial Agonist for the Treatment of Nonalcoholic Steatohepatitis | 이화정; 김대기; 권영주; 최선; 박서정 | Article |
2022 | Discovery of an Intestine-specific FXR Partial Agonist for the Treatment of Nonalcoholic Steatohepatitis | 심소연 | Doctoral Thesis |
2014 | Discovery of N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin- 2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent | 신윤용; 이화정; 김대기 | Article |
2008 | DISTRIBUTION AND METABOLISM OF NEW ALK-5 INHIBITOR, IN-1130 | 신윤용; 김대기 | Meeting Abstract |
2008 | Effect of IN-1130, a Small Molecule Inhibitor of Transforming Growth Factor-beta Type I Receptor/Activin Receptor-Like Kinase-5, on Prostate Cancer Cells | 신윤용; 김대기 | Article |
2001 | Effect of SKI 306X, a New herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study | 노권재; 김대기 | Article |
2004 | Estrogen receptor enhances the anti proliferative effects of trichostatin a and HC-toxin in human breast cancer cells | 신윤용; 김대기 | Article |
2011 | EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung | 신윤용; 김대기 | Article |
2018 | EW-7197 eluting nano-fiber covered self-expandable metallic stent to prevent granulation tissue formation in a canine urethral model | 김대기 | Article |
2014 | EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling | 신윤용; 김대기; 우현애 | Article in Press |
2014 | EW-7197, a novel ALK-5 kinase inhibitor, potently inhibits breast to lung metastasis | 신윤용; 김대기 | Article |
2017 | EW-7197, an activin-like kinase 5 inhibitor, suppresses granulation tissue after stent placement in rat esophagus | 김대기 | Article |
2018 | EW-7197, an oral transforming growth factor beta type I receptor kinase inhibitor, for preventing peritoneal adhesion formation in a rat model | 김대기 | Article |
2011 | EW-7203, a novel small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor/activin receptor-like kinase-5, blocks TGF-β1-mediated epithelial-to-mesenchymal transition in mammary epithelial cells | 신윤용; 김대기 | Article |
2007 | Glia-dependent TGF-β signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis | 김대기 | Article |
2004 | HDAC inhibitor stimulate CYP3A4 proximal activity in Hepa I and HepG2 cells | 신윤용; 김대기 | Meeting Abstract |
2004 | Histone deacetylase inhibitor stimulate CYP3A4 proximal promoter activity in HepG2 cells | 신윤용; 김대기 | Article |
2008 | Identification of human cytochrome P450 enzymes involved in the metabolism of IN-1130, a novel activin receptor-like kinase-5 (ALK5) inhibitor | 신윤용; 김대기 | Article |
2009 | IN-1130, a novel transforming growth factor-β type I receptor kinase (Activin Receptor-like Kinase 5) inhibitor, promotes regression of fibrotic plaque and corrects penile curvature in a rat model of Peyronie's disease | 김대기 | Article |
2006 | IN-1130, a novel transforming growth factor-β type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy | 신윤용; 김대기 | Article |
2010 | IN-1233, an ALK-5 inhibitor: Prevention of granulation tissue formation after bare metallic stent placement in a rat urethral model | 김대기 | Article |
2013 | IN-1233-eluting covered metallic stent to prevent hyperplasia: Experimental study in a rabbit esophageal model | 김대기 | Article |