2007 | 3D-QSAR studies on sildenafil analogues, selective phosphodiesterase 5 inhibitors | 김대기 | Article |
2014 | 4-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5(3)-(6-methylpyridin-2-yl)imidazole and -pyrazole derivatives as potent and selective inhibitors of transforming growth factor-β type i receptor kinase | 신윤용; 김대기 | Article |
2012 | A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2 | 김대기; 권영주; 전규연 | Article |
2013 | Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes | 김대기 | Article |
2023 | Aloe-derived nanovesicles attenuate inflammation and enhance tight junction proteins for acute colitis treatment | 서원효 | Article |
2009 | Altered bone morphogenetic protein and transforming growth factor-β signaling in rat models of pulmonary hypertension. Potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease | 김대기 | Article |
2014 | An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial-mesenchymal transition | 신윤용; 김대기 | Article |
2005 | Analysis of PTEN gene mutations in Korean patients with Cowden syndrome and polyposis syndrome | 정성애 | Article |
2012 | Anti-cancer effect of IN-2001 in MDA-MB-231 human breast cancer | 신윤용; 김대기 | Article |
2012 | Anti-cancer effect of in-2001 in T47D human breast cancer | 신윤용; 김대기 | Article |
2015 | Antitubercular activities of the novel synthesized 1,2,4-triazole derivatives | 신윤용; 박혜영; 김대기 | Article |
1997 | Biological effects of drug-loaded biodegradable membranes for guided bone regeneration | 이승진 | Article |
2015 | Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells | 신윤용; 김대기; 임우성 | Article |
2018 | Consensus guidelines for the definition of the end stage of disease and last days of life and criteria for medical judgment | 권복규 | Review |
2004 | Design, synthesis, and biological evaluation of novel 2-pyridinyl-[1,2,4] triazoles as inhibitors of transforming growth factor β1 type 1 receptor | 김대기 | Article |
2007 | Development of LC/MS/MS assay for the determination of 5-ethyl-2-{5-[4-(2-hydroxyethyl)piperazine-1-sulfonyl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one (SK3530) in human plasma: application to a clinical pharmacokinetic study | 김대기 | Article |
2023 | Different routes of administering EW-7197 versus EW-7197⋅HBr for preventing peritoneal adhesion in a rat model | 김대기 | Article |
2014 | Discovery of N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin- 2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent | 신윤용; 이화정; 김대기 | Article |
2001 | Effect of SKI 306X, a New herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study | 노권재; 김대기 | Article |
2011 | EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung | 신윤용; 김대기 | Article |
2022 | EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation | 심소연 | Article |
2014 | EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling | 신윤용; 김대기; 우현애 | Article in Press |
2014 | EW-7197, a novel ALK-5 kinase inhibitor, potently inhibits breast to lung metastasis | 신윤용; 김대기 | Article |
2017 | EW-7197, an activin-like kinase 5 inhibitor, suppresses granulation tissue after stent placement in rat esophagus | 김대기 | Article |
2011 | EW-7203, a novel small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor/activin receptor-like kinase-5, blocks TGF-β1-mediated epithelial-to-mesenchymal transition in mammary epithelial cells | 신윤용; 김대기 | Article |
2009 | Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner | 오구택 | Article |
2007 | Glia-dependent TGF-β signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis | 김대기 | Article |
2008 | Identification of human cytochrome P450 enzymes involved in the metabolism of IN-1130, a novel activin receptor-like kinase-5 (ALK5) inhibitor | 신윤용; 김대기 | Article |
2009 | IN-1130, a novel transforming growth factor-β type I receptor kinase (Activin Receptor-like Kinase 5) inhibitor, promotes regression of fibrotic plaque and corrects penile curvature in a rat model of Peyronie's disease | 김대기 | Article |
2006 | IN-1130, a novel transforming growth factor-β type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy | 신윤용; 김대기 | Article |