Browsing byAuthorKim D.-K.

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Showing results 1 to 30 of 59

Issue DateTitleAuthor(s)Type
20073D-QSAR studies on sildenafil analogues, selective phosphodiesterase 5 inhibitors김대기Article
20144-([1,2,4]Triazolo[1,5-a]pyridin-6-yl)-5(3)-(6-methylpyridin-2-yl)imidazole and -pyrazole derivatives as potent and selective inhibitors of transforming growth factor-β type i receptor kinase신윤용; 김대기Article
2012A-62176, a potent topoisomerase inhibitor, inhibits the expression of human epidermal growth factor receptor 2김대기; 권영주; 전규연Article
2013Activin receptor-like kinase5 inhibition suppresses mouse melanoma by ubiquitin degradation of Smad4, thereby derepressing eomesodermin in cytotoxic T lymphocytes김대기Article
2023Aloe-derived nanovesicles attenuate inflammation and enhance tight junction proteins for acute colitis treatment서원효Article
2009Altered bone morphogenetic protein and transforming growth factor-β signaling in rat models of pulmonary hypertension. Potential for activin receptor-like kinase-5 inhibition in prevention and progression of disease김대기Article
2014An novel inhibitor of TGF-β type I receptor, IN-1130, blocks breast cancer lung metastasis through inhibition of epithelial-mesenchymal transition신윤용; 김대기Article
2005Analysis of PTEN gene mutations in Korean patients with Cowden syndrome and polyposis syndrome정성애Article
2012Anti-cancer effect of IN-2001 in MDA-MB-231 human breast cancer신윤용; 김대기Article
2012Anti-cancer effect of in-2001 in T47D human breast cancer신윤용; 김대기Article
2015Antitubercular activities of the novel synthesized 1,2,4-triazole derivatives신윤용; 박혜영; 김대기Article
1997Biological effects of drug-loaded biodegradable membranes for guided bone regeneration이승진Article
2015Combinatorial TGF-β attenuation with paclitaxel inhibits the epithelial-to-mesenchymal transition and breast cancer stem-like cells신윤용; 김대기; 임우성Article
2018Consensus guidelines for the definition of the end stage of disease and last days of life and criteria for medical judgment권복규Review
2004Design, synthesis, and biological evaluation of novel 2-pyridinyl-[1,2,4] triazoles as inhibitors of transforming growth factor β1 type 1 receptor김대기Article
2007Development of LC/MS/MS assay for the determination of 5-ethyl-2-{5-[4-(2-hydroxyethyl)piperazine-1-sulfonyl]-2-propoxyphenyl}-7-propyl-3,5-dihydropyrrolo[3,2-d]pyrimidin-4-one (SK3530) in human plasma: application to a clinical pharmacokinetic study김대기Article
2023Different routes of administering EW-7197 versus EW-7197⋅HBr for preventing peritoneal adhesion in a rat model김대기Article
2014Discovery of N-((4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-5-(6-methylpyridin- 2-yl)-1H-imidazol-2-yl)methyl)-2-fluoroaniline (EW-7197): A highly potent, selective, and orally bioavailable inhibitor of TGF-β type I receptor kinase as cancer immunotherapeutic/antifibrotic agent신윤용; 이화정; 김대기Article
2001Effect of SKI 306X, a New herbal anti-arthritic agent, in patients with osteoarthritis of the knee: a double-blind placebo controlled study노권재; 김대기Article
2011EW-7195, a novel inhibitor of ALK5 kinase inhibits EMT and breast cancer metastasis to lung신윤용; 김대기Article
2022EW-7197 Attenuates the Progression of Diabetic Nephropathy in db/db Mice through Suppression of Fibrogenesis and Inflammation심소연Article
2014EW-7197 inhibits hepatic, renal, and pulmonary fibrosis by blocking TGF-β/Smad and ROS signaling신윤용; 김대기; 우현애Article in Press
2014EW-7197, a novel ALK-5 kinase inhibitor, potently inhibits breast to lung metastasis신윤용; 김대기Article
2017EW-7197, an activin-like kinase 5 inhibitor, suppresses granulation tissue after stent placement in rat esophagus김대기Article
2011EW-7203, a novel small molecule inhibitor of transforming growth factor-β (TGF-β) type I receptor/activin receptor-like kinase-5, blocks TGF-β1-mediated epithelial-to-mesenchymal transition in mammary epithelial cells신윤용; 김대기Article
2009Fenofibrate differentially regulates plasminogen activator inhibitor-1 gene expression via adenosine monophosphate-activated protein kinase-dependent induction of orphan nuclear receptor small heterodimer partner오구택Article
2007Glia-dependent TGF-β signaling, acting independently of the TH17 pathway, is critical for initiation of murine autoimmune encephalomyelitis김대기Article
2008Identification of human cytochrome P450 enzymes involved in the metabolism of IN-1130, a novel activin receptor-like kinase-5 (ALK5) inhibitor신윤용; 김대기Article
2009IN-1130, a novel transforming growth factor-β type I receptor kinase (Activin Receptor-like Kinase 5) inhibitor, promotes regression of fibrotic plaque and corrects penile curvature in a rat model of Peyronie's disease김대기Article
2006IN-1130, a novel transforming growth factor-β type I receptor kinase (ALK5) inhibitor, suppresses renal fibrosis in obstructive nephropathy신윤용; 김대기Article

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