Complementary Interventions Using Technology for Individuals With Infertility Using Assisted Reproductive Technology: A Scoping Review

Abstract

The global rise in infertility highlights the need for personalized informational and psychological support. Digital health technology offers a promising avenue; however, knowledge gaps remain regarding optimal delivery methods, outcomes, and limitations. This scoping review synthesizes recent evidence on complementary interventions using technology for individuals with infertility undergoing reproductive technology-assisted interventions and evaluates their effectiveness and limitations. Seven databases were systematically searched to identify studies published in English or Korean between 2000 and December 2023. The risk of bias was assessed using the Joanna Briggs Institute checklist, and data were synthesized using a standardized template. Of 1353 screened studies, 16 were selected, featuring interventions such as web-based programs, mobile applications, and online meetings. Positive outcomes were observed in knowledge, stress reduction, self-efficacy, coping, and dietary behaviors. However, mixed results were found for fertility-related stress, depression, and anxiety, with no significant improvements in fertility-related quality of life, health behaviors, and pregnancy rates. While digital interventions show promise, further research is needed to validate their effectiveness through large-scale randomized controlled trials and to develop standardized assessment tools for better implementation and evaluation. © 2025 Elsevier B.V., All rights reserved.