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dc.contributor.author박시재-
dc.date.accessioned2018-12-07T16:30:20Z-
dc.date.available2018-12-07T16:30:20Z-
dc.date.issued2017-
dc.identifier.issn0960-8524-
dc.identifier.otherOAK-21501-
dc.identifier.urihttps://dspace.ewha.ac.kr/handle/2015.oak/247279-
dc.description.abstractThis study examined nine expired industrial Corynebacterium glutamicum strains with high lysine producing capability for enhanced production of 5-AVA. C. glutamicum KCTC 1857 exhibiting the highest lysine production was transformed with either original Pseudomonas putida davBA genes, encoding the 5-AVA biosynthesis pathway, or C. glutamicum codon-optimized davBA genes. C. glutamicum KCTC 1857 expressing the original genes had superior cell viability and 5-AVA production capability compared to the other strain. This strain produced 39.93 g/L of 5-AVA, which is the highest titer reported to date in fed-batch fermentation from glucose. Indeed, Miscanthus hydrolysate solution prepared from a novel process, comprising pretreatment, hydrolysis, purification, and concentration, was used as feedstock for 5-AVA production. A total of 12.51 g/L 5-AVA was produced from the Miscanthus hydrolysate; this value is 34.7% higher than that obtained from glucose in batch fermentation. © 2017 Elsevier Ltd-
dc.languageEnglish-
dc.publisherElsevier Ltd-
dc.subject5-Aminovaleric acid-
dc.subjectCorynebacterium glutamicum-
dc.subjectMetabolic engineering-
dc.subjectMiscanthus-
dc.subjectPretreatment-
dc.titleProduction of 5-aminovaleric acid in recombinant Corynebacterium glutamicum strains from a Miscanthus hydrolysate solution prepared by a newly developed Miscanthus hydrolysis process-
dc.typeArticle-
dc.relation.volume245-
dc.relation.indexSCIE-
dc.relation.indexSCOPUS-
dc.relation.startpage1692-
dc.relation.lastpage1700-
dc.relation.journaltitleBioresource Technology-
dc.identifier.doi10.1016/j.biortech.2017.05.131-
dc.identifier.wosidWOS:000413038300048-
dc.identifier.scopusid2-s2.0-85020107107-
dc.author.googleJoo J.C.-
dc.author.googleOh Y.H.-
dc.author.googleYu J.H.-
dc.author.googleHyun S.M.-
dc.author.googleKhang T.U.-
dc.author.googleKang K.H.-
dc.author.googleSong B.K.-
dc.author.googlePark K.-
dc.author.googleOh M.-K.-
dc.author.googleLee S.Y.-
dc.author.googlePark S.J.-
dc.contributor.scopusid박시재(57191670770)-
dc.date.modifydate20210929141221-
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엘텍공과대학 > 화학신소재공학전공 > Journal papers
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