Full metadata record
DC Field | Value | Language |
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dc.contributor.author | 임수미 | - |
dc.contributor.author | 이보은 | - |
dc.date.accessioned | 2024-08-26T16:30:03Z | - |
dc.date.available | 2024-08-26T16:30:03Z | - |
dc.date.issued | 2024 | - |
dc.identifier.issn | 2093-9043 | - |
dc.identifier.other | OAK-35849 | - |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/269302 | - |
dc.description.abstract | Purpose: This multicenter prospective study aimed to evaluate the quality and diagnostic effectiveness of cerebral angiography images obtained using low-concentration iodinated contrast agents (iohexol 240 mgI/mL, iopamidol 250 mgI/mL, and iodixanol 270 mgI/mL) and to assess the safety thereof. The study addresses the need for safer contrast agent alternatives without compromising the diagnostic quality of identifying cerebrovascular disease. Materials and Methods: Conducted in 5 medical centers in South Korea, we enrolled patients aged 19 years or older who were referred for diagnostic cerebral angiography under non-emergency conditions, excluding those with specific health conditions and sensitivities. The study design included a prospective, observational approach with a 1-way analysis of variance (ANOVA) for sample size calculation, aiming for a total sample of 231 participants for adequate power. Image quality was evaluated using a 4-level scale by 2 independent, blind-ed radiologists, and adverse reactions were monitored both immediately and up to 7 days post-procedure. Statistical analysis involved 1-way ANOVA and Kruskal–Wallis tests to assess the image quality and safety profiles of the contrast agents. Results: Among 266 patients screened, 243 were included in the final analysis. The evaluation revealed no statistically significant differences in image quality among the 3 types of low-con-centration contrast agents. Adverse events were observed in 28.8% of patients, with 27.2% experiencing acute reactions, primarily mild reactions, and 3.3% experiencing delayed reactions. The overall safety profile showed no significant changes in vital signs or electrocardiogram readings before and after contrast agent injection. Conclusion: Using low-concentration iodinated contrast agents for cerebral angiography provides image quality comparable to that of conventional high-concentration agents, with no significant increase in adverse events, suggesting a safer alternative for patients. © 2024 Korean Society of Interventional Neuroradiology. | - |
dc.description.sponsorship | Korean Society of Interventional Neuroradiology | - |
dc.language | English | - |
dc.subject | Cerebral angiography | - |
dc.subject | Contrast media | - |
dc.subject | Diagnostic imaging | - |
dc.subject | Iohexol | - |
dc.subject | Iopamidol | - |
dc.subject | Safety | - |
dc.title | Comparison of Safety and Diagnostic Efficacy of Iohexo240 mgI/mL, Iopamidol 250 mgI/mL, and Iodixanol 270 mgI/mL in Cerebral Angiography: A Prospective, Multicenter Study | - |
dc.type | Article | - |
dc.relation.issue | 2 | - |
dc.relation.volume | 19 | - |
dc.relation.index | SCOPUS | - |
dc.relation.index | KCI | - |
dc.relation.startpage | 82 | - |
dc.relation.lastpage | 91 | - |
dc.relation.journaltitle | Neurointervention | - |
dc.identifier.doi | 10.5469/neuroint.2024.00129 | - |
dc.identifier.scopusid | 2-s2.0-85197400054 | - |
dc.author.google | Baek | - |
dc.author.google | Jinwook | - |
dc.author.google | Jeong | - |
dc.author.google | Hae Woong | - |
dc.author.google | Heo | - |
dc.author.google | Young Jin | - |
dc.author.google | Yun | - |
dc.author.google | Suyoung | - |
dc.author.google | Kang | - |
dc.author.google | Myongjin | - |
dc.author.google | Kim | - |
dc.author.google | Byungjun | - |
dc.author.google | Eui Jong | - |
dc.author.google | Lim | - |
dc.author.google | Soo Mee | - |
dc.author.google | Lee | - |
dc.author.google | Boeun | - |
dc.contributor.scopusid | 임수미(26643435000) | - |
dc.date.modifydate | 20240826111516 | - |