Aggregation-Induced Emission (AIE), Life and Health

Abstract

Light has profoundly impacted modern medicine and healthcare,withnumerous luminescent agents and imaging techniques currently beingused to assess health and treat diseases. As an emerging concept inluminescence, aggregation-induced emission (AIE) has shown great potentialin biological applications due to its advantages in terms of brightness,biocompatibility, photostability, and positive correlation with concentration.This review provides a comprehensive summary of AIE luminogens appliedin imaging of biological structure and dynamic physiological processes,disease diagnosis and treatment, and detection and monitoring of specificanalytes, followed by representative works. Discussions on criticalissues and perspectives on future directions are also included. Thisreview aims to stimulate the interest of researchers from differentfields, including chemistry, biology, materials science, medicine,etc., thus promoting the development of AIE in the fields of lifeand health.