Block Copolymer Enabled Synthesis and Assembly of Chiral Metal Oxide Nanoparticle

Abstract

Chiral metal oxide nanostructures have received tremendous attention in nanotechnological applications owing to their intriguing chiroptical and magnetic properties. Current synthetic methods mostly rely on the use of amino acids or peptides as chiral inducers. Here, we report a general approach to fabricate chiral metal oxide nanostructures with tunable magneto-chiral effects, using block copolymer (BCP) inverse micelle and R/S-mandelic acid (MA). Diverse chiral metal oxide nanostructures are prepared by the selective incorporation of precursors within micellar cores followed by the oxidation process, exhibiting intense chiroptical properties with a g-factor up to 7.0 × 10-3 in the visible-NIR range for the Cr2O3 nanoparticle multilayer. The BCP inverse micelle is found to inhibit the racemization of MA, allowing MA to act as a chiral dopant that imparts chirality to nanostructures via hierarchical chirality transfer. Notably, for paramagnetic nanostructures, magneto-chiroptical modulation is realized by regulating the direction of the external magnetic field. This BCP-driven approach can be extended to the mass production of chiral nanostructures with tunable architectures and optical activities, which may provide insights into the development of chiroptical functional materials. © 2023 American Chemical Society.