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Observing hydrogen sulfide in the endoplasmic reticulum of cancer cells and zebrafish by using an activity-based fluorescent probe
- Title
- Observing hydrogen sulfide in the endoplasmic reticulum of cancer cells and zebrafish by using an activity-based fluorescent probe
- Authors
- Kafuti, Yves S. S.; Zeng, Shuang; Liu, Xiaosheng; Han, Jingjing; Qian, Ming; Chen, Qixian; Wang, Jingyun; Peng, Xiaojun; Yoon, Juyoung; Li, Haidong
- Ewha Authors
- 윤주영
- SCOPUS Author ID
- 윤주영
- Issue Date
- 2023
- Journal Title
- CHEMICAL COMMUNICATIONS
- ISSN
- 1359-7345
1364-548X
- Citation
- CHEMICAL COMMUNICATIONS vol. 59, no. 17, pp. 2493 - 2496
- Publisher
- ROYAL SOC CHEMISTRY
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- A crucial endogenous signaling chemical, hydrogen sulfide, is involved in many physiological actions. In this work, we created the fluorescent probe ER-Nap-NBD using a naphthalimide fluorophore as the signal reporter, a 7-nitro-1,2,3-benzoxadiazole amine as the responsive moiety, and a sulfonamide part for endoplasmic reticulum targeting. ER-Nap-NBD could be detected the H2S levels in solution and in living systems (cells and zebrafish).
- DOI
- 10.1039/d2cc06645a
- Appears in Collections:
- 자연과학대학 > 화학·나노과학전공 > Journal papers
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