Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김준수 | * |
dc.date.accessioned | 2023-02-17T16:30:08Z | - |
dc.date.available | 2023-02-17T16:30:08Z | - |
dc.date.issued | 2022 | * |
dc.identifier.issn | 2470-0045 | * |
dc.identifier.issn | 2470-0053 | * |
dc.identifier.other | OAK-32922 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/263961 | - |
dc.description.abstract | Brownian motion subject to a periodic and asymmetric potential can be biased by external, nonequilibrium fluctuations, leading to directional movement of Brownian particles. Sequence-dependent flexibility variation along double-stranded DNA has been proposed as a tool to develop periodic and asymmetric potentials for DNA binding of cationic nanoparticles with sizes below tens of nanometers. Here, we propose that repetitive stretching and relaxation of a long, double-stranded DNA molecule with periodic flexibility gradient can induce nonequilibrium fluctuations that tune the amplitude of asymmetric potentials for DNA-nanoparticle binding to result in directional transport of nanometer-sized particles along DNA. Realization of the proposed Brownian ratchet was proven by Brownian dynamics simulations of coarse-grained models of a single, long DNA molecule with flexibility variation and a cationic nanoparticle. | * |
dc.language | English | * |
dc.publisher | AMER PHYSICAL SOC | * |
dc.title | Brownian ratchet for directional nanoparticle transport by repetitive stretch-relaxation of DNA | * |
dc.type | Article | * |
dc.relation.issue | 5 | * |
dc.relation.volume | 106 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.journaltitle | PHYSICAL REVIEW E | * |
dc.identifier.doi | 10.1103/PhysRevE.106.054117 | * |
dc.identifier.wosid | WOS:000907201500005 | * |
dc.author.google | Oh, Inrok | * |
dc.author.google | Song, Jeongeun | * |
dc.author.google | Hyun, Hye Ree | * |
dc.author.google | Lee, Sang Hak | * |
dc.author.google | Kim, Jun Soo | * |
dc.contributor.scopusid | 김준수(23670121600) | * |
dc.date.modifydate | 20240215165024 | * |