Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 남상집 | * |
dc.date.accessioned | 2021-08-12T16:31:50Z | - |
dc.date.available | 2021-08-12T16:31:50Z | - |
dc.date.issued | 2021 | * |
dc.identifier.issn | 1523-7060 | * |
dc.identifier.other | OAK-29483 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/258715 | - |
dc.description.abstract | Dumulmycin (1) was isolated from Streptomyces sp. DM28, a bacterial strain from a riverine sediment sample. The structure of 1 was elucidated as a bicyclic macrolide possessing 19-membered and 5-membered rings by spectroscopic analysis. The stereochemistry of 1 was determined by J-based configuration analysis, ROESY NMR data, DP4 calculations, and the modified Mosher's method. Genetic analysis identified a trans-acyltransferase polyketide biosynthetic gene cluster for 1. Dumulmycin exhibited in vitro antitubercular activity (MIC50 = 27.1 μM). © 2021 American Chemical Society. | * |
dc.language | English | * |
dc.publisher | American Chemical Society | * |
dc.title | Dumulmycin, an antitubercular bicyclic macrolide from a riverine sediment-derived streptomyces sp. | * |
dc.type | Article | * |
dc.relation.issue | 9 | * |
dc.relation.volume | 23 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 3359 | * |
dc.relation.lastpage | 3363 | * |
dc.relation.journaltitle | Organic Letters | * |
dc.identifier.doi | 10.1021/acs.orglett.1c00847 | * |
dc.identifier.wosid | WOS:000649477300025 | * |
dc.identifier.scopusid | 2-s2.0-85106162085 | * |
dc.author.google | An J.S. | * |
dc.author.google | Shin B. | * |
dc.author.google | Kim T.H. | * |
dc.author.google | Hwang S. | * |
dc.author.google | Shin Y.-H. | * |
dc.author.google | Cui J. | * |
dc.author.google | Du Y.E. | * |
dc.author.google | Yi J. | * |
dc.author.google | Nam S.-J. | * |
dc.author.google | Hong S. | * |
dc.author.google | Shin J. | * |
dc.author.google | Jang J. | * |
dc.author.google | Yoon Y.J. | * |
dc.author.google | Oh D.-C. | * |
dc.contributor.scopusid | 남상집(57208839798) | * |
dc.date.modifydate | 20240220120010 | * |