Highly selective two-photon fluorescent off-on probes for imaging tyrosinase activity in living cells and tissues

Abstract

A coumarin-based two-photon (TP) fluorescent off-on probe has been developed for detecting tyrosinase activity. High selectivity, sensitivity and biocompatibility enable the probes to successfully image tyrosinase activity in live cells and tissues using TP microscopy. © The Royal Society of Chemistry 2021.