Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 임경민 | * |
dc.contributor.author | 김민정 | * |
dc.date.accessioned | 2020-12-24T16:30:20Z | - |
dc.date.available | 2020-12-24T16:30:20Z | - |
dc.date.issued | 2020 | * |
dc.identifier.issn | 1323-8930 | * |
dc.identifier.issn | 1440-1592 | * |
dc.identifier.other | OAK-28485 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/255868 | - |
dc.description.abstract | Background: We aimed to evaluate the influence of cold airflow from the air conditioner on skin barrier function and filaggrin degradation products (FDPs) in children with atopic deramtitis (AD). Methods: In a case-control study, 28 children with AD and 12 normal children without AD were exposed to one of two air conditioner modes (conventional or wind-free) for 2 h. Skin temperature, transepidermal water loss (TEWL), and skin pH were measured on right cheek and forearm at pre- and post-exposure time points. We also measured filaggrin and FDPs from the volar surface of the forearm. Results: In AD patients, skin temperature on the forearm decreased after exposure to the conventional and wind-free modes (P < 0.001 and P = 0.026), and TEWL on the cheek and the forearm decreased in the wind-free mode (P = 0.037 and 0.002). Skin pH on the cheek increased only after exposure to the conventional mode in AD group (P = 0.002). However, no changes in TEWL and skin pH were found after exposure to either the conventional or the wind-free mode in the control group. In AD children, the levels of pyrrolidone carboxylic acid (PCA) and cis-urocanic acid (UCA) were reduced only after exposure to the conventional mode (all P = 0.033). The percent changes of PCA and cis-UCA were higher in the AD group than those in the control group after exposure to conventional mode (P = 0.029 and 0.046). Conclusions: Skin barrier function in children with AD may be altered by the exposure to cold airflow from a conventional air conditioner. Copyright (C) 2019, Japanese Society of Allergology. Production and hosting by Elsevier B.V. | * |
dc.language | English | * |
dc.publisher | JAPANESE SOCIETY ALLERGOLOGY | * |
dc.subject | Air movements | * |
dc.subject | Atopic dermatitis | * |
dc.subject | Environmental impact | * |
dc.subject | Filaggrin | * |
dc.subject | Wind | * |
dc.title | Exposure to cold airflow alters skin pH and epidermal filaggrin degradation products in children with atopic dermatitis | * |
dc.type | Article | * |
dc.relation.issue | 3 | * |
dc.relation.volume | 69 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 429 | * |
dc.relation.lastpage | 436 | * |
dc.relation.journaltitle | ALLERGOLOGY INTERNATIONAL | * |
dc.identifier.doi | 10.1016/j.alit.2019.11.004 | * |
dc.identifier.wosid | WOS:000607902400012 | * |
dc.identifier.scopusid | 2-s2.0-85076960526 | * |
dc.author.google | Jung, Minyoung | * |
dc.author.google | Kim, Insung | * |
dc.author.google | Lee, Ji Young | * |
dc.author.google | Kim, Hyun Mi | * |
dc.author.google | Kwon, Mijeong | * |
dc.author.google | Kim, Minjeong | * |
dc.author.google | Lim, Kyung-Min | * |
dc.author.google | Kim, Peter S. | * |
dc.author.google | Ahn, Kangmo | * |
dc.author.google | Kim, Jihyun | * |
dc.contributor.scopusid | 임경민(8916551700) | * |
dc.contributor.scopusid | 김민정(56999341200) | * |
dc.date.modifydate | 20240304134025 | * |