View : 70 Download: 0

Two-photon imaging of hydrogen polysulfides in living cells and hippocampal tissues

Title
Two-photon imaging of hydrogen polysulfides in living cells and hippocampal tissues
Authors
Chung J.Li H.Lim C.S.Kim H.M.Yoon J.
Ewha Authors
윤주영
SCOPUS Author ID
윤주영scopus
Issue Date
2020
Journal Title
Sensors and Actuators, B: Chemical
ISSN
0925-4005JCR Link
Citation
Sensors and Actuators, B: Chemical vol. 322
Keywords
Cell imagingFluorescent probeHydrogen polysulfidesTwo-photon
Publisher
Elsevier B.V.
Indexed
SCIE; SCOPUS scopus
Document Type
Article
Abstract
Hydrogen polysulfide (H2Sn) is an emerging topic of research because it plays a critical role in the pathological and physiological activities of an organism. Therefore, visual monitoring of H2Sn activity in living cells is critical. In our work, a two-photon fluorescent probe NI-H2S2 based on a naphthalimide skeleton was developed as a molecular tool for detecting hydrogen polysulfides in solution and live HeLa cells. NI-H2S2 showed rapid response and high sensitivity. Notably, hydrogen polysulfides in hippocampal tissue of mice could also be tracked using the probe under a two-photon fluorescence microscope. Therefore, this probe NI-H2S2 is expected to serve as a pragmatic tool for studying the physiological roles of hydrogen polysulfides in living cells and in vivo. © 2020 Elsevier B.V.
DOI
10.1016/j.snb.2020.128564
Appears in Collections:
자연과학대학 > 화학·나노과학전공 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE