View : 555 Download: 0
Clinical Manifestation and Risk Factors Associated With Remission in Patients With Filamentary Keratitis
- Title
- Clinical Manifestation and Risk Factors Associated With Remission in Patients With Filamentary Keratitis
- Authors
- Lee S.M.; Jun R.M.; Choi K.-R.; Han K.E.
- Ewha Authors
- 최규룡; 전루민; 한경은
- SCOPUS Author ID
- 최규룡; 전루민; 한경은
- Issue Date
- 2020
- Journal Title
- American Journal of Ophthalmology
- ISSN
- 0002-9394
- Citation
- American Journal of Ophthalmology vol. 218, pp. 78 - 83
- Publisher
- Elsevier Inc.
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- Purpose: This study investigated the clinical manifestation and risk factors associated with remission in filamentary keratitis. Design: Retrospective, interventional, comparative case series. Methods: We retrospectively reviewed the medical records of 116 patients with filamentary keratitis diagnosed and treated between January 2012 and December 2018. We investigated the 5 causative factors including brain lesion, dry eye syndrome, autoimmune disease, ocular surgery or injury, and other conditions; treatment methods and duration; and remission status, and analyzed the risk factors associated with remission. Results: The mean age of the patients was 56.9 ± 19.1 years and the mean follow-up duration was 14.9 ± 22.8 months. The most common underlying condition associated with filamentary keratitis was identified as a brain lesion (36.2%), followed by dry eye syndrome (30.2%) and autoimmune disease (24.1%). A comparison of remission rates among the causative factors revealed that cases associated with brain lesions had significantly lower remission rates (33.3%) than those associated with other causative factors (>60%) (P = .001). After adjustment for sex, age, diabetes mellitus, and hypertension, the treatment failure rate in patients affected by brain lesions was 6.602-fold higher than that associated without brain lesion (P = .001). The treatment method–dependent differences in the remission rate were observed in brain lesion and dry eye syndrome (P = .041 and P = .005, respectively). Conclusions: The most common condition leading to filamentary keratitis was a brain lesion, followed by dry eye syndrome and autoimmune disease. The treatment failure rate was statistically significantly low only in patients with filamentary keratitis associated with brain lesions. © 2020 Elsevier Inc.
- DOI
- 10.1016/j.ajo.2020.05.037
- Appears in Collections:
- 의과대학 > 의학과 > Journal papers
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML