Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최규룡 | * |
dc.contributor.author | 전루민 | * |
dc.contributor.author | 한경은 | * |
dc.date.accessioned | 2020-08-13T16:30:06Z | - |
dc.date.available | 2020-08-13T16:30:06Z | - |
dc.date.issued | 2020 | * |
dc.identifier.issn | 0002-9394 | * |
dc.identifier.other | OAK-27301 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/254893 | - |
dc.description.abstract | Purpose: This study investigated the clinical manifestation and risk factors associated with remission in filamentary keratitis. Design: Retrospective, interventional, comparative case series. Methods: We retrospectively reviewed the medical records of 116 patients with filamentary keratitis diagnosed and treated between January 2012 and December 2018. We investigated the 5 causative factors including brain lesion, dry eye syndrome, autoimmune disease, ocular surgery or injury, and other conditions; treatment methods and duration; and remission status, and analyzed the risk factors associated with remission. Results: The mean age of the patients was 56.9 ± 19.1 years and the mean follow-up duration was 14.9 ± 22.8 months. The most common underlying condition associated with filamentary keratitis was identified as a brain lesion (36.2%), followed by dry eye syndrome (30.2%) and autoimmune disease (24.1%). A comparison of remission rates among the causative factors revealed that cases associated with brain lesions had significantly lower remission rates (33.3%) than those associated with other causative factors (>60%) (P = .001). After adjustment for sex, age, diabetes mellitus, and hypertension, the treatment failure rate in patients affected by brain lesions was 6.602-fold higher than that associated without brain lesion (P = .001). The treatment method–dependent differences in the remission rate were observed in brain lesion and dry eye syndrome (P = .041 and P = .005, respectively). Conclusions: The most common condition leading to filamentary keratitis was a brain lesion, followed by dry eye syndrome and autoimmune disease. The treatment failure rate was statistically significantly low only in patients with filamentary keratitis associated with brain lesions. © 2020 Elsevier Inc. | * |
dc.language | English | * |
dc.publisher | Elsevier Inc. | * |
dc.title | Clinical Manifestation and Risk Factors Associated With Remission in Patients With Filamentary Keratitis | * |
dc.type | Article | * |
dc.relation.volume | 218 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 78 | * |
dc.relation.lastpage | 83 | * |
dc.relation.journaltitle | American Journal of Ophthalmology | * |
dc.identifier.doi | 10.1016/j.ajo.2020.05.037 | * |
dc.identifier.wosid | WOS:000574919700009 | * |
dc.identifier.scopusid | 2-s2.0-85088636511 | * |
dc.author.google | Lee S.M. | * |
dc.author.google | Jun R.M. | * |
dc.author.google | Choi K.-R. | * |
dc.author.google | Han K.E. | * |
dc.contributor.scopusid | 최규룡(7403949263) | * |
dc.contributor.scopusid | 전루민(6602278519) | * |
dc.contributor.scopusid | 한경은(37031161100) | * |
dc.date.modifydate | 20240422130207 | * |