View : 648 Download: 0
Bio-Conjugated Advanced Materials for Targeted Disease Theranostics
- Title
- Bio-Conjugated Advanced Materials for Targeted Disease Theranostics
- Authors
- Hu, Xi-Le; Kwon, Nahyun; Yan, Kai-Cheng; Sedgwick, Adam C.; Chen, Guo-Rong; He, Xiao-Peng; James, Tony D.; Yoon, Juyoung
- Ewha Authors
- 윤주영
- SCOPUS Author ID
- 윤주영
- Issue Date
- 2020
- Journal Title
- ADVANCED FUNCTIONAL MATERIALS
- ISSN
- 1616-301X
1616-3028
- Citation
- ADVANCED FUNCTIONAL MATERIALS vol. 30, no. 13
- Keywords
- advanced materials; aptamers; biomolecules; peptides; theranostics
- Publisher
- WILEY-V C H VERLAG GMBH
- Indexed
- SCIE; SCOPUS
- Document Type
- Review
- Abstract
- Human beings are "machines" that use endogenously produced biomolecules as "components" in signaling and for the maintenance of the body. These biomolecules consist of proteins, nucleic acids, and carbohydrates, which can either be extracted from biological substrates or synthesized by chemical/biochemical methods. These biomolecules have the ability to recognize/interact with other biomolecules that are overexpressed in disease cells. For targeted theranostics, strategies to chemically incorporate these natural biomolecules with advanced materials to treat human diseases by imaging-guided drug delivery or photodynamic/photothermal therapy are proposed, with improved biocompatibility. Herein, recent research on construction of quantum dots, nanoparticles, and 2D material platforms decorated with antibodies, peptides, nucleic acid aptamers, carbohydrates, and folic acid for targeted diagnosis and treatment are summarized and discussed. In addition, the various strategies required to construct effective functional materials for targeted cancer therapy are highlighted. The hope is that this review can inspire and guide those that are interested in the field of biomedicine to rationally design and develop new target-based theranostic materials.
- DOI
- 10.1002/adfm.201907906
- Appears in Collections:
- 자연과학대학 > 화학·나노과학전공 > Journal papers
- Files in This Item:
There are no files associated with this item.
- Export
- RIS (EndNote)
- XLS (Excel)
- XML