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Nano theranostics platforms that utilize proteins
- Title
- Nano theranostics platforms that utilize proteins
- Authors
- Lee, Songyi; Thanh Chung Pham; Bae, Chaeeon; Choi, Yeonghwan; Kim, Yong Kyun; Yoon, Juyoung
- Ewha Authors
- 윤주영
- SCOPUS Author ID
- 윤주영
- Issue Date
- 2020
- Journal Title
- COORDINATION CHEMISTRY REVIEWS
- ISSN
- 0010-8545
1873-3840
- Citation
- COORDINATION CHEMISTRY REVIEWS vol. 412
- Keywords
- Protein-based theranostics; Drug delivery; Phototherapy; Bioimaging; Imaging-guided cancer therapy
- Publisher
- ELSEVIER SCIENCE SA
- Indexed
- SCIE; SCOPUS
- Document Type
- Review
- Abstract
- Proteins have received increasing attention as a novel platform for drug delivery and phototheranostic agents that may serve as new nanomedicines. In drug delivery system, proteins can act as powerful tools with self-assembled structures, triggering groups, receptors and agents to enhance cell penetration. Compared to other nanoparticle based theranostics, nano-platforms for theranostics by utilizing proteins have unique merits, such as higher loading capacities and high efficiency of photosensitizers in phototherapies. However, the full potential of protein-based theranostics has not been achieved thus far. In this review, recent advances made in this area were discussed following a format based on proteins in drug delivery systems, proteins-dye complexes for phototherapy of cancer, proteins nanoparticles for imaging-guided cancer therapy such as fluorescent imaging, positron emission tomography (PET), magnetic resonance imaging (MRI), ultrasound (US) Imaging, PA imaging and proteins-based nanoprobes and nanostructures. Importantly, this discussion also provides a view of future advances that will likely be made in this area and their potential clinical applications. (C) 2020 Elsevier B.V. All rights reserved.
- DOI
- 10.1016/j.ccr.2020.213258
- Appears in Collections:
- 자연과학대학 > 화학·나노과학전공 > Journal papers
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