View : 41 Download: 0

Adjuvant incorporated lipid nanoparticles for enhanced mRNA-mediated cancer immunotherapy

Title
Adjuvant incorporated lipid nanoparticles for enhanced mRNA-mediated cancer immunotherapy
Authors
Lee, KyuriKim, Soo YoungSeo, YunmiKim, Myung HeeChang, JunLee, Hyukjin
Ewha Authors
장준이혁진이규리
SCOPUS Author ID
장준scopus; 이혁진scopus
Issue Date
2020
Journal Title
BIOMATERIALS SCIENCE
ISSN
2047-4830JCR Link

2047-4849JCR Link
Citation
BIOMATERIALS SCIENCE vol. 8, no. 4, pp. 1101 - 1105
Publisher
ROYAL SOC CHEMISTRY
Indexed
SCIE; SCOPUS WOS scopus
Document Type
Article
Abstract
For mRNA mediated cancer immunotherapy, Pam3 was incorporated as an adjuvant within lipid nanoparticles (LNPs) with OVA mRNA. The developed Pam3 incorporated LNPs showed successful expression of tumor antigens with enhanced immune stimulation. We demonstrated that the synergies of Pam3 LNPs could greatly improve the efficacy of tumor prevention by mRNA vaccines.
DOI
10.1039/c9bm01564g
Appears in Collections:
약학대학 > 약학과 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE