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Synthetic ratiometric fluorescent probes for detection of ions

Title
Synthetic ratiometric fluorescent probes for detection of ions
Authors
Park, Sang-HyunKwon, NahyunLee, Jee-HyeonYoon, JuyoungShin, Injae
Ewha Authors
윤주영
SCOPUS Author ID
윤주영scopus
Issue Date
2020
Journal Title
CHEMICAL SOCIETY REVIEWS
ISSN
0306-0012JCR Link

1460-4744JCR Link
Citation
CHEMICAL SOCIETY REVIEWS vol. 49, no. 1, pp. 143 - 179
Publisher
ROYAL SOC CHEMISTRY
Indexed
SCI; SCIE; SCOPUS WOS scopus
Document Type
Review
Abstract
Metal cations and anions are essential for versatile physiological processes. Dysregulation of specific ion levels in living organisms is known to have an adverse effect on normal biological events. Owing to the pathophysiological significance of ions, sensitive and selective methods to detect these species in biological systems are in high demand. Because they can be used in methods for precise and quantitative analysis of ions, organic dye-based ratiometric fluorescent probes have been extensively explored in recent years. In this review, recent advances (2015-2019) made in the development and biological applications of synthetic ratiometric fluorescent probes are described. Particular emphasis is given to organic dye-based ratiometric fluorescent probes that are designed to detect biologically important and relevant ions in cells and living organisms. Also, the fundamental principles associated with the design of ratiometric fluorescent probes and perspectives about how to expand their biological applications are discussed.
DOI
10.1039/c9cs00243j
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자연과학대학 > 화학·나노과학전공 > Journal papers
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