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CNR improvement of MP2RAGE from slice encoding directional acceleration

Title
CNR improvement of MP2RAGE from slice encoding directional acceleration
Authors
Shin, WanyongShin, TaehoonOh, Se-HongLowe, Mark J.
Ewha Authors
신태훈
Issue Date
2016
Journal Title
MAGNETIC RESONANCE IMAGING
ISSN
0730-725XJCR Link

1873-5894JCR Link
Citation
MAGNETIC RESONANCE IMAGING vol. 34, no. 6, pp. 779 - 784
Keywords
MP2RAGEMPRAGE2D accelerationSPIRiTultra-high filed7 T
Publisher
ELSEVIER SCIENCE INC
Indexed
SCI; SCIE; SCOPUS WOS
Document Type
Article
Abstract
Purpose: While MP2RAGE shows the potential to generate B-1 insensitive T-1 contrast, the long TR of MP2RAGE (>= 6 s at 7 T) is essential to provide the large dynamic range of apparent T-1 relaxation for dual inversion time acquisitions. We present a 2 direction (2D) accelerated MP2RAGE, which provides an increased flip angle while maintaining similar dynamic recovery as 1D accelerated MP2RAGE. Method: Simulations were conducted to optimize 2D accelerated MP2RAGE parameters and healthy subjects were scanned with 1D and 2D accelerated MP2RAGE at 7 T. Images were compared visually and contrast to noise (CNR) between brain tissues was measured. Result: Simulations showed that CNR is primarly determined by the TR, followed by the number of the first partition encoding steps in MP2RAGE. Keeping TR constant, a smaller number of partition encoding steps increases the achievable maximal CNR. In-vivo 2D MP2RAGE improves CNR between white and gray matters by 9% when compared to 1D accelerated MP2RAGE with identical voxel size. Conclusion: We presented 2D accelated MP2RAGE at 7 T with the increased flip angle. We show that this leads to CNR improvement, and consequently a reduction of scan time to be compared to 1D accelerated MP2RAGE. (C) 2016 Elsevier Inc. All rights reserved.
DOI
10.1016/j.mri.2016.03.014
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엘텍공과대학 > 휴먼기계바이오공학부 > Journal papers
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