View : 34 Download: 0

Portable, one-step, and rapid GMR biosensor platform with smartphone interface

Title
Portable, one-step, and rapid GMR biosensor platform with smartphone interface
Authors
Choi, JoohongGani, Adi WijayaBechstein, Daniel J. B.Lee, Jung-RokUtz, Paul J.Wang, Shan X.
Ewha Authors
이정록
Issue Date
2016
Journal Title
BIOSENSORS & BIOELECTRONICS
ISSN
0956-5663JCR Link

1873-4235JCR Link
Citation
BIOSENSORS & BIOELECTRONICS vol. 85, pp. 1 - 7
Keywords
Point of carePortable and rapid diagnosticsSmartphone integrationGMR sensorOne-step magnetic immunoassayMagnetic nanoparticle
Publisher
ELSEVIER ADVANCED TECHNOLOGY
Indexed
SCI; SCIE; SCOPUS WOS
Document Type
Article
Abstract
Quantitative immunoassay tests in clinical laboratories require trained technicians, take hours to complete with multiple steps, and the instruments used are generally immobile-patient samples have to be sent in to the labs for analysis. This prevents quantitative immunoassay tests to be performed outside laboratory settings. A portable, quantitative immunoassay device will be valuable in rural and resource limited areas, where access to healthcare is scarce or far away. We have invented Eigen Diagnosis Platform (EDP), a portable quantitative immunoassay platform based on Giant Magnetoresistance (GMR) biosensor technology. The platform does not require a trained technician to operate, and only requires one-step user involvement. It displays quantitative results in less than 15 min after sample insertion, and each test costs less than US$4. The GMR biosensor employed in EDP is capable of detecting multiple biomarkers in one test, enabling a wide array of immune diagnostics to be performed simultaneously. In this paper, we describe the design of EDP, and demonstrate its capability. Multiplexed assay of human immunoglobulin G and M (IgG and IgM) antibodies with EDP achieves sensitivities down to 0.07 and 033 nanomolar, respectively. The platform will allow lab testing to be performed in remote areas, and open up applications of immunoassay testing in other non-clinical settings, such as home, school, and office. (C) 2016 Elsevier B.V. All rights reserved.
DOI
10.1016/j.bios.2016.04.046
Appears in Collections:
엘텍공과대학 > 휴먼기계바이오공학부 > Journal papers
Files in This Item:
There are no files associated with this item.
Export
RIS (EndNote)
XLS (Excel)
XML


qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

BROWSE