Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 신태훈 | * |
dc.date.accessioned | 2019-05-03T16:30:11Z | - |
dc.date.available | 2019-05-03T16:30:11Z | - |
dc.date.issued | 2019 | * |
dc.identifier.issn | 0740-3194 | * |
dc.identifier.issn | 1522-2594 | * |
dc.identifier.other | OAK-24666 | * |
dc.identifier.uri | https://dspace.ewha.ac.kr/handle/2015.oak/249747 | - |
dc.description.abstract | Purpose: Velocity-selective saturation (VSS) pulse trains provide a viable alternative to the spatially selective methods for measuring cerebral blood volume (CBV) by reducing the sensitivity to arterial transit time. This study is to compare the Fourier-transformbased velocity-selective saturation (FT-VSS) pulse trains with the conventional flow-dephasing VSS techniques for CBV quantification. Methods: The proposed FT-VSS label and control modules were compared with VSS pulse trains utilizing double refocused hyperbolic tangent (DRHT) and 8-segment B1-insensitive rotation (BIR-8). This was done using both numerical simulations and phantom studies to evaluate their sensitivities to gradient imperfections such as eddy currents. DRHT, BIR-8, and FT-VSS prepared CBV mapping was further compared for velocity-encoding gradients along 3 orthogonal directions in healthy subjects at 3T. Results: The phantom studies exhibited more consistent immunity to gradient imperfections for the utilized FT-VSS pulse trains. Compared to DRHT and BIR-8, FT-VSS delivered more robust CBV results across the 3 VS encoding directions with significantly reduced artifacts along the superior-inferior direction and improved temporal signal-to-noise ratio (SNR) values. Average CBV values obtained from FT-VSS based sequences were 5.3 mL/100 g for gray matter and 2.3 mL/100 g for white matter, comparable to literature expectations. Conclusion: Absolute CBV quantification utilizing advanced FT-VSS pulse trains had several advantages over the existing approaches using flow-dephasing VSS modules. A greater immunity to gradient imperfections and the concurrent tissue background suppression of FT-VSS pulse trains enabled more robust CBV measurements and higher SNR than the conventional VSS pulse trains. | * |
dc.language | English | * |
dc.publisher | WILEY | * |
dc.subject | arterial spin labeling | * |
dc.subject | cerebral blood volume | * |
dc.subject | eddy current | * |
dc.subject | Fourier-transform-based velocity-selective saturation | * |
dc.subject | velocity-selective pulse train | * |
dc.title | Cerebral blood volume mapping using Fourier-transform-based velocity-selective saturation pulse trains | * |
dc.type | Article | * |
dc.relation.issue | 6 | * |
dc.relation.volume | 81 | * |
dc.relation.index | SCIE | * |
dc.relation.index | SCOPUS | * |
dc.relation.startpage | 3544 | * |
dc.relation.lastpage | 3554 | * |
dc.relation.journaltitle | MAGNETIC RESONANCE IN MEDICINE | * |
dc.identifier.doi | 10.1002/mrm.27668 | * |
dc.identifier.wosid | WOS:000481978700010 | * |
dc.identifier.scopusid | 2-s2.0-85061278268 | * |
dc.author.google | Qin, Qin | * |
dc.author.google | Qu, Yaoming | * |
dc.author.google | Li, Wenbo | * |
dc.author.google | Liu, Dapeng | * |
dc.author.google | Shin, Taehoon | * |
dc.author.google | Zhao, Yansong | * |
dc.author.google | Lin, Doris D. | * |
dc.author.google | van Zijl, Peter C. M. | * |
dc.author.google | Wen, Zhibo | * |
dc.contributor.scopusid | 신태훈(15061749900) | * |
dc.date.modifydate | 20240322132527 | * |