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자연과학대학
화학·나노과학전공
Journal papers
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A two-photon ESIPT based fluorescence probe for specific detection of hypochlorite
Title
A two-photon ESIPT based fluorescence probe for specific detection of hypochlorite
Authors
Chen L.
;
Park S.J.
;
Wu D.
;
Kim H.M.
;
Yoon J.
Ewha Authors
윤주영
SCOPUS Author ID
윤주영
Issue Date
2018
Journal Title
Dyes and Pigments
ISSN
0143-7208
Citation
Dyes and Pigments vol. 158, pp. 526 - 532
Keywords
ESIPT
;
Hypochlorite
;
Living cells
;
Tissue imaging
;
Two-photon
Publisher
Elsevier Ltd
Indexed
SCIE; SCOPUS
Document Type
Article
Abstract
Hypochlorous acid (HOCl) is one important member of reactive oxygen species (ROS) familyresponsible for various human diseases. Although many contributions have been made to develop fluorescent probes for sensing HOCl, many of them suffer small Stokes shifts, sophisticated synthetic procedure, and slow reaction rate. In the current study, we designed and synthesized an ESIPT based fluorescence probe with diaminomeleonitrile (DMN) as reactive site. The probe can detect HOCl with high selectivity and sensitivity. It also has large Stokes shift and rapid reaction rate. Moreover, it can be utilized to monitor exogenous and endogenous HOCl in living cells and tissues via two-photon microscopy. © 2018 Elsevier Ltd
DOI
10.1016/j.dyepig.2018.01.027
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