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One-pot three component synthesis of 5-allyl-1,2,3-triazoles using copper(i) acetylides
- Title
- One-pot three component synthesis of 5-allyl-1,2,3-triazoles using copper(i) acetylides
- Authors
- Reddy P.R.; Cui L.; Ryu J.-S.
- Ewha Authors
- 류재상
- SCOPUS Author ID
- 류재상
- Issue Date
- 2018
- Journal Title
- RSC Advances
- ISSN
- 2046-2069
- Citation
- RSC Advances vol. 8, no. 5, pp. 2759 - 2767
- Publisher
- Royal Society of Chemistry
- Indexed
- SCIE; SCOPUS
- Document Type
- Article
- Abstract
- One-pot three-component reactions using copper(i) acetylide, azide, allyl iodide, and NaOH have been developed. The reactions proceed smoothly at room temperature to afford 5-allyl-1,2,3-triazoles, which can be further transformed into a variety of 1,2,3-triazole-fused bi-/tricyclic scaffolds. This method offers the most efficient, convenient, and practical route towards useful polycyclic scaffolds in moderate to excellent yields. © The Royal Society of Chemistry 2018.
- DOI
- 10.1039/c7ra12889d
- Appears in Collections:
- 약학대학 > 약학과 > Journal papers
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