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Antimicrobial activity of a conjugated polymer with cationic backbone

Title
Antimicrobial activity of a conjugated polymer with cationic backbone
Authors
Xu Q.He P.Wang J.Chen H.Lv F.Liu L.Wang S.Yoon J.
Ewha Authors
윤주영Qingling Xu
SCOPUS Author ID
윤주영scopus
Issue Date
2019
Journal Title
Dyes and Pigments
ISSN
0143-7208JCR Link
Citation
vol. 160, pp. 519 - 523
Keywords
AntimicrobialCationic backboneConjugated polymerImidazolium
Publisher
Elsevier Ltd
Indexed
SCI; SCIE; SCOPUS scopus
Abstract
Owing to the misuse of antibiotics and slow development of new drugs, antibiotic-resistant pathogens have become a serious threat to human health. With the aim of developing new antimicrobial agents, we designed and synthesized a new conjugated polymer (PFPhim), which possesses an imidazolium containing backbone. The cationic backbone enables it to strongly interact with bacterial membrane leading to an antimicrobial ability that is more potent than that of a conjugated polymer containing a neutral backbone. PFPhim also displays strong photodynamic antimicrobial activity. © 2018 Elsevier Ltd
DOI
10.1016/j.dyepig.2018.08.049
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자연과학대학 > 화학·나노과학전공 > Journal papers
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