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Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando

Title
Bioactive prenylated flavonoids from the stem bark of Artocarpus kemando
Authors
Seo E.-K.Lee D.Young G.S.Chai H.-B.Navarro H.A.Kardono L.B.S.Rahman I.Cordell G.A.Farnsworth N.R.Pezzuto J.M.Kinghorn A.D.Wani M.C.Wall M.E.
Ewha Authors
서은경
SCOPUS Author ID
서은경scopus
Issue Date
2003
Journal Title
Archives of Pharmacal Research
ISSN
0253-6269JCR Link
Citation
vol. 26, no. 2, pp. 124 - 127
Indexed
SCIE; SCOPUS; KCI scopus
Abstract
Four known prenylated flavonoids, artonins E (1) and O (2), artobiloxanthone (3), and cycloartobiloxanthone (4), were isolated from the stem bark of Artocarpus kemando by bioassay-guided fractionation using the DNA strand-scission and the KB cytotoxicity assays as monitors. Compounds 1 and 3 exhibited strong DNA strand-scission activity, and all four compounds were found to be cytotoxic.
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약학대학 > 약학과 > Journal papers
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