PURPOSE: The purpose of this research was to examine the effects of exercise program on knowledge and attitude of exercise, and depression in low-income elderly women. METHOD: The research design was a nonequivalent control group pretest-posttest design. The subjects were 26 in the experimental group and 22 in the control group among 46 low-income women over age 65. The independent variable is the exercise program, and the dependent variables are knowledge and attitude of exercise and depression. The exercise program was performed for 45-50 minutes, twice a week for 8 weeks. Data was collected from March 12. to May 8. 2004. RESULT: Participants were given a pre-test and post-test for the selected variables. The experimental group reported significant improvements in their knowledge and attitude of exercise and depression scores compared with the control group. CONCLUSION: The results indicated that the exercise program had the potential to manage low-income elderly women's health promotion. Furthermore, the exercise program can enhance life satisfaction in low-income elderly women.