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The metabolism of xylazine in rats

Title
The metabolism of xylazine in rats
Authors
Park Choo H.-Y.Choi S.-O.
Ewha Authors
박혜영
SCOPUS Author ID
박혜영scopus
Issue Date
1991
Journal Title
Archives of Pharmacal Research
ISSN
0253-6269JCR Link
Citation
Archives of Pharmacal Research vol. 14, no. 4, pp. 346 - 351
Indexed
SCIE; SCOPUS; KCI scopus
Document Type
Article
Abstract
The biotransformation of xylazine, a widly used animal tranquilizer, was investigated in rats. After administration of xylazine, the existence of 2,6-dimethylphenylisothiocyanate, 2,6-dimenthyl-4-hydroxy-aniline and p-hydroxy-xylazine in urine was confirmed by the comparison with chemically prepared standards in GC/MS. The main metabolite, p-hydroxy xylazine was excreted as conjugated form.
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약학대학 > 약학과 > Journal papers
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