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GM3 affects carboxyl methylation in the human erythrocyte membrane

Title
GM3 affects carboxyl methylation in the human erythrocyte membrane
Authors
Yoon H.-J.Park H.-J.Jhon G.-J.
Ewha Authors
전길자
SCOPUS Author ID
전길자scopus
Issue Date
1992
Journal Title
Biochemistry International
ISSN
0158-5231JCR Link
Citation
Biochemistry International vol. 28, no. 3, pp. 393 - 399
Indexed
SCOPUS scopus
Document Type
Article
Abstract
Effects of gangliosides in human erythrocyte membrane using carboxyl methyltransferase have been investigated. As GM3 concentration increased, methylatability for membrane was increased. But bovine brain ganglioside mixture did not alter methylatability even at a higher concentration. When 30μM of GM3 was used in erythrocyte membrane, methylatability was increased by 32%. When purified-glucose transporters were reconstituted into egg phosphatidylcholine-liposome with GM3, methylatability was increased by 37%. Thus conformational difference of membrane according to localization of GM3 in intact human erythrocyte membrane or liposome possibly increases the methylatability and activity of glucose transporter itself.
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자연과학대학 > 화학·나노과학전공 > Journal papers
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