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Effect of ethyl alcohol fraction of Cervus nippon on mouse T-lymphocyte

Title
Effect of ethyl alcohol fraction of Cervus nippon on mouse T-lymphocyte
Authors
Jeon K.-J.Suh J.-S.Oh C.-H.Yum J.-Y.Eun J.-S.
Ewha Authors
전길자
SCOPUS Author ID
전길자scopus
Issue Date
1998
Journal Title
Korean Journal of Pharmacognosy
ISSN
0253-3073JCR Link
Citation
Korean Journal of Pharmacognosy vol. 29, no. 4, pp. 312 - 317
Indexed
SCOPUS; KCI scopus
Document Type
Article
Abstract
In this study, the effect of 70% ethyl alcohol fraction of Cervus nippon (CN-E) on mouse T-lymphocyte was investigated in vivo. The administration of CN-E (100 mg/kg) enhanced the proliferation of thymocytes, the population of CD4+ CD8- single-positive cells and the production of interferon-γ in thymocytes and splenocytes. The administration of CN-E did not induce DNA fragmentation and reduce mitochondrial transmembrane potential in thymocytes. These results indicate that the CN-E contains a stimulative component on the proliferation of thymocytes, the population of T(H) cells and the production of interferon-γ in T-lymphocytes.
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자연과학대학 > 화학·나노과학전공 > Journal papers
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