DSpace at EWHA: Effect of oryung-san, a Korean traditional diuretic, on the pharmacokinetics of intravenous cefazolin in rats

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DC Field	Value	Language
dc.contributor.author	구영순	*
dc.contributor.author	이정연	*
dc.date.accessioned	2018-06-02T08:15:00Z	-
dc.date.available	2018-06-02T08:15:00Z	-
dc.date.issued	1999	*
dc.identifier.issn	1087-1101	*
dc.identifier.other	OAK-17114	*
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/244353	-
dc.description.abstract	The effect of oryung-san (OS), a Korean traditional diuretic, on the renal excretion of intravenous cefazolin (CEZ) was investigated in rats. In OS-pre-treated rats, the cumulative 6-hr urinary excretion of cefazolin was significantly greater (4460 versus 3340 μg) and renal clearance was significantly faster (7.74 versus 4.90 ml/min/kg). This could be due to increase in unbound fraction of cefazolin in plasma and significant increase in cumulative 6-hr urine output (6.20 versus 3.96 ml) in OS-pretreated rats.	*
dc.language	English	*
dc.title	Effect of oryung-san, a Korean traditional diuretic, on the pharmacokinetics of intravenous cefazolin in rats	*
dc.type	Article	*
dc.relation.issue	1-2	*
dc.relation.volume	4	*
dc.relation.index	SCOPUS	*
dc.relation.startpage	95	*
dc.relation.lastpage	103	*
dc.relation.journaltitle	Research Communications in Pharmacology and Toxicology	*
dc.identifier.scopusid	2-s2.0-0032697591	*
dc.author.google	Rhie J.-Y.	*
dc.author.google	Young Soon Ku	*
dc.contributor.scopusid	구영순(7202602602)	*
dc.contributor.scopusid	이정연(57191753089)	*
dc.date.modifydate	20240220111424	*