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Evaluation of the antioxidant potential of Korean indigenous plant extracts by free radical scavenging activity
- Title
- Evaluation of the antioxidant potential of Korean indigenous plant extracts by free radical scavenging activity
- Authors
- Kim Y.; Min H.-Y.; Park E.-J.; Lee Y.S.; Jin C.; Lee S.K.
- Ewha Authors
- 이상국
- SCOPUS Author ID
- 이상국
- Issue Date
- 2003
- Journal Title
- Natural Product Sciences
- ISSN
- 1226-3907
- Citation
- Natural Product Sciences vol. 9, no. 2, pp. 80 - 82
- Indexed
- SCOPUS; KCI
- Document Type
- Article
- Abstract
- Since reactive oxygen radicals play an important role in carcinogenesis and other human diseases including neurodegenerative states, antioxidants present in natural products have received considerable attention for alleviation of these disease states. Therefore, in order to identify antioxidants in plant extracts, fifty-seven methanolic extracts derived from indigenous Korean plants were primarily assessed for potential to scavenge stable 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals. As a result, nine plant extracts were found to exhibit the DPPH free radical scavenging activity in the criteria of IC50 <40 μg/ml. In particular, the extracts of Melioma oldhami (IC50 = 0.1 μg/ml), Myrica rubra (IC50 = 16.2 μg/ml), Sympolocos paniculata (IC50 = 23.0 μg/ml) Carpinus laxiflora (IC50 = 25.1 μg/ml), and Cleyera japonica (IC50 = 26.2 μg/ml) showed a potent radical scavenging activity. Further study for the identification of active compounds from these lead extracts might be warranted.
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- 약학대학 > 약학과 > Journal papers
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