DSpace at EWHA: Synthesis of 3'-ureidoadenosines and their high binding affinity at the mutant A3 adenosine receptor.

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DC Field	Value	Language
dc.contributor.author	이강만	-
dc.contributor.author	정낙신	-
dc.date.accessioned	2018-06-02T08:13:52Z	-
dc.date.available	2018-06-02T08:13:52Z	-
dc.date.issued	2005	-
dc.identifier.issn	1746-8272	-
dc.identifier.other	OAK-17912	-
dc.identifier.uri	https://dspace.ewha.ac.kr/handle/2015.oak/243903	-
dc.description.abstract	For the purpose of developing optimal neoceptor-neoagonist pair, 3'-ureidoadenosine derivatives were synthesized. Among compounds tested, 2-chloro-3'-ureido-N6-(3-iodobenzyl)adenosine (10b) showed the best binding affinity (Ki = 0.20 microM) at the H272E mutant A3 AR, but was inactive at the natural A3 AR.	-
dc.language	English	-
dc.title	Synthesis of 3'-ureidoadenosines and their high binding affinity at the mutant A3 adenosine receptor.	-
dc.type	Article	-
dc.relation.issue	49	-
dc.relation.index	SCOPUS	-
dc.relation.startpage	105	-
dc.relation.lastpage	106	-
dc.relation.journaltitle	Nucleic acids symposium series (2004)	-
dc.identifier.scopusid	2-s2.0-39049175931	-
dc.author.google	Kim A.Y.	-
dc.author.google	Kim H.O.	-
dc.author.google	Kim M.J.	-
dc.author.google	Chun M.W.	-
dc.author.google	Lee K.M.	-
dc.author.google	Jacobson K.A.	-
dc.author.google	Jeong L.S.	-
dc.contributor.scopusid	이강만(7501506362)	-
dc.contributor.scopusid	정낙신(16028528200)	-
dc.date.modifydate	20211210153610	-